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This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 6-0 Fast-Absorbing Gut Suture | Experimental | Two 6-0 fast-absorbing gut sutures were placed in the skin of deltoid, randomized to site A/B for the control (uncoated) and intervention (petrolatum coated) suture. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Petrolatum coating of fast-absorbing gut suture | Device | 6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid |
| Measure | Description | Time Frame |
|---|---|---|
| Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture. | Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture. | Postprocedurally daily until suture is degraded (less than 2 weeks) |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29723559 | Result | Susong JR, Neiner JR. Effect of petrolatum coating on fast-absorbing gut suture. J Am Acad Dermatol. 2018 Nov;79(5):952-953. doi: 10.1016/j.jaad.2018.04.041. Epub 2018 Apr 30. No abstract available. |
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