Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Parenteral Lactated Ringer's Plus Dextrose 5% vs Lactated Ringer's in Labor: A Randomized Control Trial on Maternal and Neonatal Outcomes

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are:

1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers?
2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Inclusion Criteria:

• Nulliparous women
• Age 18 years or older and able to provide informed consent
• Singleton pregnancy at term
• Induction of labor
• Cephalic presentation
• Unfavorable cervix (Bishop score ≤ 6)

Exclusion Criteria:

• Age under 18 years
• Involuntarily confined or detained
• Considered as having diminished decision-making capacity
• Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned
• Favorable cervix (Bishop score >6)
• Diabetes mellitus (both gestational and pre-gestational)
• Structural renal disease
• Acute or chronic kidney disease resulting in abnormal creatinine or proteinuria
• Evidence of chorioamnionitis or non-reassuring fetal testing at the time of enrollment
• Pyrexia (>38.0 degrees Celsius)
• Stillbirth
• Planned cesarean delivery
• Women presenting with emergent circumstances for labor induction