Integrating HIV Prevention With TB Household Contact Evaluation in Uganda

Integrating HIV Prevention With TB Household Contact Evaluation in Uganda (TB PrEP)

This household randomized implementation study assesses the implementation and effectiveness of home-based HIV self- testing and PrEP initiation versus standard clinic referral for PrEP initiation during modified standard-of-care (modified SOC) household TB contact investigation in Uganda. It uses qualitative methods to evaluate the process of implementing the intervention and a health economic evaluation to assess the financial sustainability of this strategy.

Inclusion Criteria:

• Person with pulmonary TB OR live in a household with someone with pulmonary TB being treated at one of the participating health facilities
• Household includes ≥2 persons
• Age 15 years and older
• Willingness to participate in study procedures

Exclusion Criteria:

• Lives in a congregate setting (e.g., dormitory or jail)
• Lives outside the study area
• Any other condition that, in the opinion of the Investigator/designee, could preclude informed consent, make study participation unsafe, or otherwise interfere with achieving study objectives