Memory Deterioration in Alzheimer Disease

Translational Neuroscience CAG for Alzheimer's Disease

Semantic AD

Inclusion Criteria:

• Confirmed diagnosis based on current ICD criteria for AD or MCI .
• >55years.
• Norwegian native speaker
• Lives at home and not in a health institution

Exclusion Criteria:

• Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR > 2).

• Presence of brain tumors.

• History of traumatic brain injury.

• History of cranial surgery.

• Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).

• Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.

  7T MRI contraindications:

• Large tattoos close to the head region, permanent makeup or unremoveable piercings

• Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)

• Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)