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| ID | Type | Description | Link |
|---|---|---|---|
| R34DA062367 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Drug Abuse (NIDA) | NIH |
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To develop an intervention that engages family members in supporting HIV and opioid substitution therapy treatment for those who inject drugs in South Africa, and then conduct a pilot study to understand feasibility and preliminary impact on outcomes.
In response to increased injection drug use in Johannesburg, South Africa, and low ART and OST treatment retention rates, we will develop and pilot-test the intervention, Project Vuselela. The intervention is designed to engage family members in treatment support using a multi-session skill-building approach that is led by trained peer navigators. Both PLWHIDs and their family members will attend sessions to develop these skills and treatment action plans, facilitated by peer navigators. We will assess PLWHID and family acceptability of the intervention and preliminary impact on PLWHID ART and OST treatment adherence when compared to those in the current program as standard of care. The study will be conducted at Yeoville Clinic in Johannesburg, a setting with high rates of injection drug use and the only OST clinic in the city.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | Four sessions on coping and communication skills to improve support for treatment among family members and people who inject drugs. |
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| Standard of Care | No Intervention | Offered current harm reduction services at clinics. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Project Vuselela | Behavioral | A four session intervention with people who inject drugs and family members. Delivered three group sessions and one dyad session. Session content designed to improve coping and communication skills that will in turn improve treatment outcomes. |
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of the intervention | Assess feasibility, acceptability, willingness and safety. This will be completed using in-depth interviews and a study-specific survey. | 3 and 6 months |
| Antiretroviral Therapy Therapy (ART) Adherence | Medical chart review of monthly anti-retroviral therapy (ART) prescription refill data will be collected. ART is medication to manage HIV infection. | 3 and 6 months |
| Opioid Substitution Therapy (OST) Adherence | Medical chart review of opioid substitution therapy (OST) pick-up. This measure assesses use of OST to reduce effects of addiction. | 3 and 6 months |
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Inclusion Criteria:
Aim 2 PLHWID Inclusion Criteria
Family Member Inclusion Criteria
Exclusion Criteria:
PLHWID Exclusion Criteria
Family Member Exclusion Criteria
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Joseph A Daniels, PhD | Contact | 206 459 5777 | Joseph.A.Daniels@asu.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anova Health Institute | Recruiting | Johannesburg | South Africa |
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| ID | Term |
|---|---|
| D000076064 | Drug Misuse |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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Pilot study to understand intervention feasibility and preliminary impact on HIV and OST outcomes.
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