Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| RTF1201 | Other Grant/Funding Number | Wellbeing of Women | |
| RTF1201 | Other Grant/Funding Number | The Burdett Trust for Nursing |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Wellbeing of Women | OTHER |
| Burdett Trust for Nursing | OTHER |
Not provided
Not provided
Not provided
Not provided
In the UK, approximately 6000 women every year undergo caesarean sections with general anaesthetic. Additionally, around 1300 women are admitted to Intensive Care Units (ICU) annually, typically due to pregnancy or childbirth complications. Some of these women are admitted to ICU for critical care immediately following a general anaesthetic caesarean section. However, there is little research on the impact of these experiences on women/birthing people and their families.
This project aims to explore the impact of general anaesthetic caesarean section, with or without subsequent ICU admission, on a mother's mental health and bonding with her newborn. Women and birthing people who have undergone a caesarean section with an epidural or spinal anaesthesia can also take part in this study, so that outcomes can be compared for different types of caesarean birth.
Birth is a dynamic and transformative event, both on an individual and societal level and a key phase in the transition to motherhood. Many women or birthing people remain conscious during childbirth, allowing for immediate interaction and bonding activities with their newborns. However, those who undergo a General Anaesthetic Caesarean Section (GACS) are in a state of controlled unconsciousness due the effects of the general anaesthetic and therefore, will not experience their infant being born or early post-birth interactions.
Additionally, a small proportion of women or birthing people require admission to Intensive Care Units (ICU) following GACS. This can result in more prolonged periods where the mother is unable to emotionally connect or interact with her newborn. Consequently, this may increase the risk of mental health issues and affect bonding experiences for the mother postnatally. Yet, the impact of these events on women and their families remains largely underexplored.
This study Involves a longitudinal survey to collect prospective data on the experience of GACS compared to caesarean sections with neuraxial anaesthesia (NACS), focusing on mental health outcomes and maternal-infant bonding. The survey will include the Depression, Anxiety & Stress Scale (DASS-21), the City Birth Trauma Scale (CBTS) and the Postpartum Bonding Questionnaire (PBQ) and one question on self-harm from the Edinburgh Postnatal Depression Scale (EPDS). These measures will be collected upon completion of the initial survey and again 3 months later.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women or birthing people who have given birth by GACS | Women or birthing people aged 18 or older who have given birth by GACS in a UK hospital, within 12 months postpartum. | ||
| Women or birthing people who have given birth by NACS | Women or birthing people aged 18 or older who have given birth by NACS in a UK hospital, within 12 months postpartum. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Postnatal depression | Depression scores (DASS-21) | 1-15 months post birth |
| Newborn bonding | PBQ scores | 1-15 months post birth |
| Measure | Description | Time Frame |
|---|---|---|
| Anxiety | Anxiety scores (DASS-21) | 1-15 months post birth |
| PTSD symptoms | City Birth Trauma Scale scores | 1-15 months post birth. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Any woman or birthing person who has undergone a caesarean section with general or neuraxial anaesthesia in a UK based hospital within 12 months postpartum.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Michelle Anderson, PhD Candidate | Contact | +447957955462 | michelle.4.anderson@kcl.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Dr Hannah Rayment-Jones | King's College London | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Life Science and Medicine | London | SE1 7EH | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32977111 | Background | Wittkowski A, Vatter S, Muhinyi A, Garrett C, Henderson M. Measuring bonding or attachment in the parent-infant-relationship: A systematic review of parent-report assessment measures, their psychometric properties and clinical utility. Clin Psychol Rev. 2020 Dec;82:101906. doi: 10.1016/j.cpr.2020.101906. Epub 2020 Sep 3. | |
| 12124409 |
| Label | URL |
|---|---|
| NIHR South London Applied Research Collaboration | View source |
Not provided
IPD will not be shared as participants do not provide consent for the sharing of their data outside the research team, even in anonymised form.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Self-harm | Scores from self-harm question on Edinburgh Postnatal Depression Scale | 1-15 months post birth |
| Wisner KL, Parry BL, Piontek CM. Clinical practice. Postpartum depression. N Engl J Med. 2002 Jul 18;347(3):194-9. doi: 10.1056/NEJMcp011542. No abstract available. |
| 30762247 | Background | Widstrom AM, Brimdyr K, Svensson K, Cadwell K, Nissen E. Skin-to-skin contact the first hour after birth, underlying implications and clinical practice. Acta Paediatr. 2019 Jul;108(7):1192-1204. doi: 10.1111/apa.14754. Epub 2019 Mar 13. |
| 15539778 | Background | Reck C, Hunt A, Fuchs T, Weiss R, Noon A, Moehler E, Downing G, Tronick EZ, Mundt C. Interactive regulation of affect in postpartum depressed mothers and their infants: an overview. Psychopathology. 2004 Nov-Dec;37(6):272-80. doi: 10.1159/000081983. Epub 2004 Nov 9. |
| 35306947 | Background | Pownall M, Hutter RRC, Rockliffe L, Conner M. Memory and mood changes in pregnancy: a qualitative content analysis of women's first-hand accounts. J Reprod Infant Psychol. 2023 Nov;41(5):516-527. doi: 10.1080/02646838.2022.2052827. Epub 2022 Mar 20. |
| 37768532 | Background | Powell DN, Leonhardt ND. A Longitudinal Examination of Mothers' Early Postnatal Adaptation: Relative Stability Across the First Eight Weeks. Matern Child Health J. 2023 Dec;27(12):2175-2184. doi: 10.1007/s10995-023-03776-4. Epub 2023 Sep 28. |
| Background | NMPA Project Team. National maternity and perinatal audit: clinical report (2019) Based on births in NHS maternity services between 1st April 2016 and 31st March 2017. Royal College of Obstetrics and Gynaecology, London 2019. NMPA Clinical Report 2019.pdf (maternityaudit.org.uk) |
| Background | NMPA Project Team. National maternity and perinatal audit: clinical report (2021) Based on births in NHS maternity services between 1st April 2017 and 31st March 2018. Royal College of Obstetrics and Gynaecology, London 2019. NMPA Clinical Report 2019.pdf (maternityaudit.org.uk). |
| 31368743 | Background | Nakic Rados S, Matijas M, Kuhar L, Andelinovic M, Ayers S. Measuring and conceptualizing PTSD following childbirth: Validation of the City Birth Trauma Scale. Psychol Trauma. 2020 Feb;12(2):147-155. doi: 10.1037/tra0000501. Epub 2019 Aug 1. |
| Background | National Maternity and Perinatal Audit Clinical Report 2022 Based on births in NHS maternity services in England and Wales between 1 April 2018 and 31 March 2019 Ref 336 NMPA Clinical Report_2022.pdf (maternityaudit.org.uk). |
| 29223210 | Background | Neczypor JL, Holley SL. Providing Evidence-Based Care During the Golden Hour. Nurs Womens Health. 2017 Dec;21(6):462-472. doi: 10.1016/j.nwh.2017.10.011. |
| 30813938 | Background | Mehra R, Shebl FM, Cunningham SD, Magriples U, Barrette E, Herrera C, Kozhimannil KB, Ickovics JR. Area-level deprivation and preterm birth: results from a national, commercially-insured population. BMC Public Health. 2019 Feb 27;19(1):236. doi: 10.1186/s12889-019-6533-7. |
| Background | Lovibond SH, Lovibond PF: Manual for the Depression Anxiety Stress Scales . 1995, Sydney , Psychology Foundation of Australia, 2nd. |
| 7726811 | Background | Lovibond PF, Lovibond SH. The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. Behav Res Ther. 1995 Mar;33(3):335-43. doi: 10.1016/0005-7967(94)00075-u. |
| 33844261 | Background | Krawczyk P, Jastrzebska A, Lipka D, Huras H. Pregnancy related and postpartum admissions to intensive care unit in the obstetric tertiary care center - an 8-year retrospective study. Ginekol Pol. 2021;92(8):575-578. doi: 10.5603/GP.a2021.0034. Epub 2021 Apr 12. |
| Background | Knight M, B. K., Tuffnell D, Shakespeare J, Kotnis R, Kenyon S, Kurinczuk. (2022). Saving Lives, Improving Mother's Care Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Morbidity 2018-2020. Retrieved from https://www.npeu.ox.ac.uk/assets/downloads/mbrrace-uk/reports/maternal-report-2022/MBRRACE-UK_Maternal_MAIN_Report_2022_v10.pdf |
| 30279671 | Background | Handelzalts JE, Hairston IS, Matatyahu A. Construct Validity and Psychometric Properties of the Hebrew Version of the City Birth Trauma Scale. Front Psychol. 2018 Sep 18;9:1726. doi: 10.3389/fpsyg.2018.01726. eCollection 2018. |
| 34580422 | Background | Grunberg VA, Geller PA, Hoffman C, Njoroge W, Ahmed A, Patterson CA. Parental mental health screening in the NICU: a psychosocial team initiative. J Perinatol. 2022 Mar;42(3):401-409. doi: 10.1038/s41372-021-01217-0. Epub 2021 Sep 27. |
| 26689770 | Background | Ferguson S, Browne J, Taylor J, Davis D. Sense of coherence and women׳s birthing outcomes: A longitudinal survey. Midwifery. 2016 Mar;34:158-165. doi: 10.1016/j.midw.2015.11.017. Epub 2015 Dec 2. |
| 38216393 | Background | Faulks F, Edvardsson K, Mogren I, Gray R, Copnell B, Shafiei T. Common mental disorders and perinatal outcomes in Victoria, Australia: A population-based retrospective cohort study. Women Birth. 2024 Mar;37(2):428-435. doi: 10.1016/j.wombi.2024.01.001. Epub 2024 Jan 12. |
| 24160774 | Background | Farr SL, Dietz PM, O'Hara MW, Burley K, Ko JY. Postpartum anxiety and comorbid depression in a population-based sample of women. J Womens Health (Larchmt). 2014 Feb;23(2):120-8. doi: 10.1089/jwh.2013.4438. Epub 2013 Oct 26. |
| 8189400 | Background | Edwards DR, Porter SA, Stein GS. A pilot study of postnatal depression following caesarean section using two retrospective self-rating instruments. J Psychosom Res. 1994 Feb;38(2):111-7. doi: 10.1016/0022-3999(94)90084-1. |
| 26410818 | Background | De Schepper S, Vercauteren T, Tersago J, Jacquemyn Y, Raes F, Franck E. Post-Traumatic Stress Disorder after childbirth and the influence of maternity team care during labour and birth: A cohort study. Midwifery. 2016 Jan;32:87-92. doi: 10.1016/j.midw.2015.08.010. Epub 2015 Sep 8. |
| 3651732 | Background | Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987 Jun;150:782-6. doi: 10.1192/bjp.150.6.782. |
| 34153532 | Background | Chantry AA, Monnet C, Fresson J, Miller D, Bonnet MP, Deneux-Tharaux C. Repeated maternal ICU admission: Results from a nationwide analysis. Anaesth Crit Care Pain Med. 2021 Oct;40(5):100905. doi: 10.1016/j.accpm.2021.100905. Epub 2021 Jun 18. |
| 33507792 | Background | Caparros-Gonzalez RA, Romero-Gonzalez B, Peralta-Ramirez MI, Ayers S, Galan-Paredes A, Caracuel-Romero A. Assessment of posttraumatic stress disorder among women after childbirth using the City Birth Trauma Scale in Spain. Psychol Trauma. 2021 Jul;13(5):545-554. doi: 10.1037/tra0001007. Epub 2021 Jan 28. |
| 16673041 | Background | Brockington IF, Fraser C, Wilson D. The Postpartum Bonding Questionnaire: a validation. Arch Womens Ment Health. 2006 Sep;9(5):233-42. doi: 10.1007/s00737-006-0132-1. Epub 2006 May 4. |
| 14751705 | Background | Brockington I. Postpartum psychiatric disorders. Lancet. 2004 Jan 24;363(9405):303-10. doi: 10.1016/S0140-6736(03)15390-1. |
| 35182820 | Background | Roxanne B, Laura VDB, Yannic VG, Natacha VC, Luka VL, Kuipers YJ. Validation of the postpartum bonding questionnaire: A cross-sectional study among Flemish mothers. Midwifery. 2022 Apr;107:103280. doi: 10.1016/j.midw.2022.103280. Epub 2022 Feb 8. |
| 33073371 | Background | Bhatia K, Columb M, Bewlay A, Eccles J, Hulgur M, Jayan N, Lie J, Verma D, Parikh R. The effect of COVID-19 on general anaesthesia rates for caesarean section. A cross-sectional analysis of six hospitals in the north-west of England. Anaesthesia. 2021 Mar;76(3):312-319. doi: 10.1111/anae.15313. Epub 2020 Nov 2. |
| 27321728 | Background | Bell AF, Andersson E. The birth experience and women's postnatal depression: A systematic review. Midwifery. 2016 Aug;39:112-23. doi: 10.1016/j.midw.2016.04.014. Epub 2016 May 7. |
| 32736825 | Background | Bamber JH, Lucas DN, Plaat F, Russell R. Obstetric anaesthetic practice in the UK: a descriptive analysis of the National Obstetric Anaesthetic Database 2009-14. Br J Anaesth. 2020 Oct;125(4):580-587. doi: 10.1016/j.bja.2020.06.053. Epub 2020 Jul 28. |
| 36893444 | Background | Bamber JH, Goldacre R, Lucas DN, Quasim S, Knight M. A national cohort study to investigate the association between ethnicity and the provision of care in obstetric anaesthesia in England between 2011 and 2021. Anaesthesia. 2023 Jul;78(7):820-829. doi: 10.1111/anae.15987. Epub 2023 Mar 9. |
| 22670573 | Background | Andersen LB, Melvaer LB, Videbech P, Lamont RF, Joergensen JS. Risk factors for developing post-traumatic stress disorder following childbirth: a systematic review. Acta Obstet Gynecol Scand. 2012 Nov;91(11):1261-72. doi: 10.1111/j.1600-0412.2012.01476.x. Epub 2012 Aug 13. |
| 30279664 | Background | Ayers S, Wright DB, Thornton A. Development of a Measure of Postpartum PTSD: The City Birth Trauma Scale. Front Psychiatry. 2018 Sep 18;9:409. doi: 10.3389/fpsyt.2018.00409. eCollection 2018. |