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| ID | Type | Description | Link |
|---|---|---|---|
| 101116047 | Other Grant/Funding Number | European Research Council |
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| Name | Class |
|---|---|
| University of Twente | OTHER |
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To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (>100 kHz).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EEG measurement during DBS | Different DBS conditions can include the individual bilateral therapeutical DBS settings, unilateral versions of these setting, unilateral single segment use of these settings or unilateral low frequency (15-30 Hz) DBS. EEG measurements with a 4-channel analog EEG amplifier (Digitimer EEG). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EEG recording | Other | EEG will be recorded at high sampling rate |
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| Measure | Description | Time Frame |
|---|---|---|
| Electric potential at the EEG locations | The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data. | during DBS |
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Inclusion Criteria:
Exclusion Criteria:
none.
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Patients implanted with deep brain stimulation
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bettina C. Schwab, PhD | Contact | +49 40 7410 26907 | b.schwab@uke.de | |
| Thomas Keizers | Contact | t.keizers@utwente.nl |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Center Hamburg-Eppendorf | Recruiting | Hamburg | 20246 | Germany |
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