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This study is investigating a potential link between a novel measurement made on cardiac ultrasound and the risk of ischemic stroke in patients with a normal heart rhythm. The novel measurement is called left atrial strain. It uses speckle tracking echocardiography to measure the muscle function of the left atrium, one of the cardiac chambers. Investigators investigated whether patients with lower function of this chamber are at a higher risk of developing stroke from blood clots traveling to the brain. It is already known that patients with an irregular heart rhythm known as atrial fibrillation are at higher risk of these types of strokes. Investigators wanted to determine if there is a similar association in patients with normal heart rhythm but low left atrial strain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with Acute Ischemic Stroke | Patients presenting to the emergency department with FAST positive symptoms who are proven to have acute ischaemic stroke on neuroimaging. | ||
| Patients without Acute Ischaemic Stroke | Patients presenting to the emergency department with FAST positive symptoms who do not have evidence of acute ischaemic stroke on neuroimaging and an alternative cause of their FAST symptoms is found |
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| Measure | Description | Time Frame |
|---|---|---|
| Correlation between left atrial strain and acute ischaemic stroke | This correlation will be adjusted for common stroke risk factors such as age, gender, hypertension, smoking, dyslipidaemia, and diabetes. | 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Patients presenting to the emergency department with FAST positive symptoms suspicious for an acute stroke.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Connolly Hospital Blanchardstown | Dublin | Co. Dublin | D15 X40D | Ireland |
Echo measurements: Left atrial strain measurements, left ventricular ejection fraction, interventricular septal thickness, E/e' Demographics: Age, gender, hypertension status, smoking status, diabetes status, dyslipidaemia status,
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| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 |
| Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |