Outcomes and Risk Factors for Liver Transplantation Using... | NCT07101718

Studies
Outcomes and Risk Factors for Liver Transplantation Using Significant Fibrotic Grafts

NCT07101718

Sponsor

Zhejiang University

Status

Completed

Last Update Posted

Aug 3, 2025Actual

Enrollment

25,419Actual

Phase

Not provided

Conditions

Liver Transplant

Interventions

No intervention

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jul 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jul 1, 2024Actual

Primary Completion Date

Jul 10, 2024Actual

Completion Date

Dec 31, 2024Actual

First Submitted Date

Jul 28, 2025

First Submission Date that Met QC Criteria

Jul 28, 2025

First Posted Date

Aug 3, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 28, 2025

Last Update Posted Date

Aug 3, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

25,419Actual

Arms/Interventions Module

Arm Groups

Label	Description	Intervention Names
No fibrotic	Liver transplant recipient receiving no fibrotic liver grafts.	Other: No intervention
Mild fibrotic	Liver transplant recipient receiving mild fibrotic liver grafts.	Other: No intervention
Significant	Liver transplant recipient receiving significant fibrotic liver grafts.	Other: No intervention

Interventions

Name	Type	Description	Arm Group Labels	Other Names
No intervention	Other	No intervention	Mild fibrotic No fibrotic Significant

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Overall survival rates	The overall survival of liver transplant recipients.	January 2015 to December 2024

Secondary Outcomes

Measure	Description	Time Frame
Graft survival rates	The graft survival of liver transplant recipients.	January 2015 to December 2024

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

patients receiving liver transplantation during the period from March 2015 to March 2024

Exclusion Criteria:

recipients under 18 years old
re-transplantation cases
multiorgan transplant cases, reduced-size or split LT cases
lacking follow-up records or graft biopsy records

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

A total of 25419 patients underwent liver transplant were studied.

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Zhejiang University school of Medicine		Hangzhou	Zhejiang	310006	China

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided