This study tracks the long-term development of premature infants to examine how birth profiles, risk factors, and physical functioning influence their activities, participation, and quality of life. It also identifies predictors of functional outcomes, evaluates assessment tool sensitivity, validates the General Movements Assessment (GMA) as a prognostic tool, and compares findings with the Taiwan Infant Development Database. The study hypothesizes that birth conditions and postnatal complications predict differences in development and well-being, that risk factors and physical function relate to participation and quality of life, and that the GMA will show reliable validity across disability categories.

1. Premature Cases

Inclusion criteria:

1. Born before 37 weeks.
2. Aged 0-3 years.
3. Caregivers consent and agree to cooperate.
4. Stable condition with regular outpatient care, medication, and rehabilitation.

Exclusion criteria:

1. Acute illness (e.g., infection).
2. Parents/caregivers unable to communicate in Chinese.

2. Full-term Cases

Inclusion criteria:

1. Born at full term.
2. Aged 0-3 years.
3. No disease affecting neurophysiological development.
4. Caregivers consent and agree to cooperate.

Exclusion criteria:

1. Medical conditions affecting neurophysiological development (e.g., traumatic brain injury).
2. Neurodevelopmental disorders
3. Sensory perception disorders
4. Chromosomal abnormalities
5. Parents/caregivers unable to communicate in Chinese.

This study will recruit 100 full-term children and 350 premature children for a longitudinal follow-up.