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| ID | Type | Description | Link |
|---|---|---|---|
| 2024-A01473-44 | Other Identifier | ID-RCB Number |
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After major surgery, fluid overload is associated with an increase of morbidity and mortality.
Fluid administration should therefore be given wisely. However, there is a paucity of monitor to predict preload dependence in paediatric anaesthesia.
The aim of this study is to determine if VTI variation, measured through the suprasternal window, with a cardiac doppler probe, can predict preload dependence.
Indeed, cardiac probe are present in most operating room and suprasternal window is reachable in most surgical case, which should allow VTI monitoring for the vast majority of our patient.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Measurement of VTI variation and cardiac output after general anaesthesia. | Measurement of VTI variation and cardiac output after general anaesthesia. Patients responding to volume expansion (more than 10% increase of cardiac output measured by transthoracic ultrasound after a 10ml/kg perfusion of cristalloids) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Measurement of aortic Vmax and VTI with suprasternal doppler. | Diagnostic Test | Measurement of aortic Vmax and VTI with suprasternal doppler. Measurement of VTI variation and cardiac output after general anaesthesia. After preoperative fasting compensation, measurement of cardiac output (CO). Search of a difference in the suprasternale VTI variability between the patients who have increased their CO after fasting compensation and the patient who haven't. |
| Measure | Description | Time Frame |
|---|---|---|
| Aortic VTI variation (%) measured by suprasternal doppler in percent of mean aortic VTI. | During preoperative, after induction and fasting compensation, before incision. |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patient (%) in whom we can use suprasternal aortic measurements. | During preoperative period, after induction and fasting compensation, before incision. | |
| Optimal threshold of aortic VTI variation (%) measured by suprasternal doppler to determine wether the patient is preload dependant or independent as defined above. |
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Inclusion Criteria:
Exclusion Criteria:
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Patient under 18 admitted to paediatric operating room for a surgical intervention, an endoscopy, an interventional radiology procedure or an imagery and needing a general anaesthesia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Martin DUBERNET, Dr | Contact | +33 3 20 44 59 62 | Martin.DUBERNET@chu-lille.fr | |
| Julien COROUGE, Dr | Contact | +33 3 20 44 59 62 | julien.corouge@chu-lille.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| chu de Lille | Recruiting | Lille | France |
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|
Optimal threshold of aortic VTI variation (%) measured by suprasternal doppler to determine wether the patient is preload dependant or independent as defined above (more than 10% increase of cardiac output measured by transthoracic ultrasound after a 10mL/kg perfusion of cristalloids OR not). |
| During preoperative period, after induction and fasting compensation, before incision. |
| Correlation between : - fasting duration in hours, determined by patient or parent interrogation. - preload dependence as defined above. More than one outcome measure appears to be described. | Correlation between :
More than one outcome measure appears to be described. | During preoperative period, after induction and fasting compensation, before incision. |