High vs Low Fall Injuries in Asia: 7-Year Multicenter Study | NCT07093658

Studies
High vs Low Fall Injuries in Asia: 7-Year Multicenter Study

NCT07093658

Sponsor

Mackay Memorial Hospital

Status

Completed

Last Update Posted

Jul 30, 2025Actual

Enrollment

59,099Actual

Phase

Not provided

Conditions

Fall Injury
Trauma

Interventions

High fall injury group

Countries

Not provided

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jul 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 1, 2016Actual

Primary Completion Date

Dec 2022Actual

Completion Date

Dec 2024Actual

First Submitted Date

Jul 23, 2025

First Submission Date that Met QC Criteria

Jul 23, 2025

First Posted Date

Jul 30, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 23, 2025

Last Update Posted Date

Jul 30, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This multicenter study revealed a declining overall incidence of fall-related injuries, accompanied by a rising proportion of high falls, predominantly among non-elderly males. Mortality risk increased significantly at fall heights of 3 and 6 meters, supporting current field triage thresholds. Across both high and low falls, lower SpO₂ and GCS were key predictors of 30-day mortality, with head injury being an additional risk factor in low fall cases

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

59,099Actual

Label	Type	Description	Intervention Names
Low fall injury group			Other: High fall injury group

Name	Type	Description	Arm Group Labels	Other Names
High fall injury group	Other	High fall injury group	Low fall injury group

Measure	Description	Time Frame
30-day mortality	30-day mortality	30-day

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

This study included adult patients (aged ≥18 years) who were transported by emergency medical services (EMS) between January 2016 and December 2022.
Fall injury patients

Exclusion Criteria:

missing data on age, sex, injury mechanism, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), oxygen saturation (SpO₂), Glasgow Coma Scale (GCS), Abbreviated Injury Scale (AIS) for each body region, Injury Severity Score (ISS), Revised Trauma Score (RTS), or fall height
missing records of 30-day mortality

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

This study included adult patients (aged ≥18 years) who were transported by emergency medical services (EMS) between January 2016 and December 2022. Patients were excluded if they had missing data on age, sex, injury mechanism, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), oxygen saturation (SpO₂), Glasgow Coma Scale (GCS), Abbreviated Injury Scale (AIS) for each body region, Injury Severity Score (ISS), Revised Trauma Score (RTS), or fall height. In addition, patients with missing records of 30-day mortality were excluded from the mortality cohort analysis.

Sampling Method

Non-Probability Sample

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
19388920	Result	Kim J, Shin SD, Im TH, Kug Jong Lee, Ko SB, Park JO, Ahn KO, Song KJ. Development and validation of the Excess Mortality Ratio-adjusted Injury Severity Score Using the International Classification of Diseases 10th Edition. Acad Emerg Med. 2009 May;16(5):454-464. doi: 10.1111/j.1553-2712.2009.00412.x.
28792281	Result