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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2025-02152 | Other Identifier | NCI Clinical Trial Reporting Program |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
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This phase III trial compares the use of a digital chatbot enabled intervention to standard remote genetic services for increasing uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing for cancer predisposition syndromes has become standard evidence-based practice and can inform enhanced screening and risk reducing measures to reduce cancer morbidity and mortality. Despite this, many AYAs are not receiving recommended genetic counseling and testing. Offering remote telehealth services can address access barriers and chatbots and texting interventions could enhance patient outcomes and reduce provider and staff time. The use of a digital chatbot enabled intervention may be equally as effective as standard remote genetic services in AYA cancer patients undergoing genetic testing.
The primary and secondary objectives of the study:
PRIMARY OBJECTIVES:
I. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to increase uptake of genetic counseling.
II. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to increase uptake of genetic testing.
SECONDARY OBJECTIVE:
I. To evaluate the efficacy of an enhanced eHealth and chatbot enabled delivery model to provide non-inferior short-term and longitudinal cognitive (e.g. knowledge), affective (e.g. distress), and behavioral outcomes (e.g. cancer screening and communication to relatives) and costs.
EXPLORATORY OBJECTIVES:
I. To test for moderators of uptake of counseling and testing (primary objectives).
II. To test for moderators of short-term and longitudinal patient outcomes (secondary objectives).
III. To identify facilitators and barriers to implementation of the enhanced eHealth and chatbot enabled delivery model and standard remote services.
OUTLINE: Patients are randomized to 1 of 2 arms. Non-patient participants are assigned to arm 3.
ARM I: Patients attend a standard of care telehealth visit with a genetic counselor for pretest genetic education. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results.
ARM II: Patients receive access to the Genetic Journey Chatbot and choose to complete digital pre-test genetic education via the digital tool or via telehealth visit with a genetic counselor. Via the chatbot, patients may request a telehealth visit with a genetic counselor at any time to answer unresolved questions. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results. The chatbot remains available to answer questions, assess barriers, and provide reminders for next steps during the testing period.
ARM III: Non-patient participants complete an interview on study.
After completion of study intervention, patients are followed up at 6 and 12 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Arm I (standard remote genetic services) | Active Comparator | Patients attend a standard of care telehealth visit with a genetic counselor for pretest genetic education. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results. |
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| Arm II (Genetic Journey Chatbot) | Experimental | Patients receive access to the Genetic Journey Chatbot and choose to complete digital pre-test genetic education via the digital tool or via telehealth visit with a genetic counselor. Via the chatbot, patients may request a telehealth visit with a genetic counselor at any time to answer unresolved questions. Patients then undergo standard of care genetic testing and attend a telehealth visit with a genetic counselor for disclosure of results. The chatbot remains available to answer questions, assess barriers, and provide reminders for next steps during the testing period. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Telemedicine | Other | Undergo telehealth visit with genetic counselor for pretest genetic education |
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| Measure | Description | Time Frame |
|---|---|---|
| Uptake of genetic counseling | Defined as a binary outcome of whether an adolescent or young adult (AYA) underwent genetic counseling within 6 months post completion of the baseline survey. Will be compared between randomized arms using Cochran-Mantel-Haenszel (CMH) tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error. | Within 6 months of baseline |
| Uptake of genetic testing | Defined as a binary outcome of whether an AYA underwent genetic testing within 6 months post completion of the baseline survey. Will be compared between randomized arms using CMH tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error. | Within 6 months of baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Knowledge of genetic disease | Obtained from the KnowGene scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 standard deviation (SD) non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. |
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rachel Wills | Contact | 773-702-9171 | cancercontrolprotocols@alliancenctn.org |
| Name | Affiliation | Role |
|---|---|---|
| Angela Bradbury, MD | Alliance for Clinical Trials in Oncology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anchorage Associates in Radiation Medicine | Recruiting | Anchorage | Alaska | 98508 | United States |
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| Genetic Testing | Other | Complete standard of care genetic testing |
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| Telemedicine | Other | Undergo telehealth visit with genetic counselor for disclosure of results |
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| Internet-Based Intervention | Other | Receive access to Genetic Journey Chatbot |
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| Educational Intervention | Other | Complete digital pre-test genetic education |
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| Patient Navigation | Behavioral | Utilize chatbot to answer questions, assess barriers, and provide reminders for next steps during the testing period |
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| Interview | Other | Complete interview |
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| Survey Administration | Other | Ancillary studies |
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| Up to 42 months post registration |
| Test result recall | Measured via the Test Result Recall scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Perceptions of genetic disease | Measured via the Perceived Risk scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Anxiety | Measured via Patient Reported Outcome Measurement Information System (PROMIS) anxiety score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Depression | Measured via PROMIS Depression score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Disease-specific distress | Measured via the Revised Impact of Events Scale score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Impact of cancer risk | Measured via the Multi-dimensional Impact of Cancer Risk Assessment score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics | Up to 42 months post registration |
| Satisfaction with genetic services | Measured via the Satisfaction with Genetic Services scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. | Up to 30 months post registration |
| Attitude toward genetic testing | Measured via Attitudes Toward Genetic Testing scale. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit or each secondary endpoint at T2 (the primary time point of interest for the secondary analyses) will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. | Up to 24 months post registration |
| Lifestyle behaviors | Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Health behaviors | Measured via the Screening Health behaviors score. Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Communication to at-risk relatives | Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 42 months post registration |
| Genetic counselor time | o Will be compared using non-inferiority testing with the equivalent of a 0.3 SD non-inferiority margin. The lower limit of the one-sided 97.5% confidence limit for the difference in means will be compared with the non-inferiority margin and non-inferiority will be concluded if the interval fully lies above -0.3 SD. Longitudinal analyses will include model based analysis using generalized linear models of endpoints over time with link function determined by distribution of the endpoint being modeled and adjusting for baseline patient and disease characteristics. | Up to 24 months post registration |
| Testing costs | Measured by 2 patient reported items | Up to 36 months post registration |
| Costs of the intervention | o Will be estimated from a societal perspective, including direct medical and nonmedical costs. These include intervention and chatbot hosting, telecommunication services, personnel and patient time. Information to estimate intervention costs collected from study billing and payment records (e.g. website hosting, chatbot usage and time, videoconferencing and phone usage) and telegenetic staff logs (personnel time). The cost of personnel time will be based on institution-specific salaries, including fringe benefits. In sensitivity analysis, will substitute site-specific salary information with national average wage rates for the relevant occupational categories. Information about other out-of-pocket costs for testing (e.g. copayments) will be obtained through participant surveys. Patient time costs will be valued using national average wage rates for participant-specified occupations. | Up to 42 months post registration |
| Alaska Breast Care and Surgery LLC | Recruiting | Anchorage | Alaska | 99508 | United States |
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| Alaska Oncology and Hematology LLC | Recruiting | Anchorage | Alaska | 99508 | United States |
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| Alaska Women's Cancer Care | Recruiting | Anchorage | Alaska | 99508 | United States |
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| Katmai Oncology Group | Recruiting | Anchorage | Alaska | 99508 | United States |
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| Providence Alaska Medical Center | Recruiting | Anchorage | Alaska | 99508 | United States |
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| Fairbanks Memorial Hospital | Recruiting | Fairbanks | Alaska | 99701 | United States |
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| Cancer Center at Saint Joseph's | Recruiting | Phoenix | Arizona | 85004 | United States |
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| Mercy Hospital Fort Smith | Recruiting | Fort Smith | Arkansas | 72903 | United States |
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| CARTI Cancer Center | Recruiting | Little Rock | Arkansas | 72205 | United States |
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| Mission Hope Medical Oncology - Arroyo Grande | Recruiting | Arroyo Grande | California | 93420 | United States |
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| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Recruiting | Burbank | California | 91505 | United States |
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| Mercy Cancer Center - Carmichael | Recruiting | Carmichael | California | 95608 | United States |
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| Mercy San Juan Medical Center | Recruiting | Carmichael | California | 95608 | United States |
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| Mercy Cancer Center - Elk Grove | Recruiting | Elk Grove | California | 95758 | United States |
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| Mercy Cancer Center | Recruiting | Merced | California | 95340 | United States |
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| Providence Queen of The Valley | Recruiting | Napa | California | 94558 | United States |
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| Mercy Cancer Center - Rocklin | Recruiting | Rocklin | California | 95765 | United States |
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| Mercy Cancer Center - Sacramento | Recruiting | Sacramento | California | 95816 | United States |
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| Pacific Central Coast Health Center-San Luis Obispo | Recruiting | San Luis Obispo | California | 93401 | United States |
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| Mission Hope Medical Oncology - Santa Maria | Recruiting | Santa Maria | California | 93444 | United States |
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| Providence Medical Foundation - Santa Rosa | Recruiting | Santa Rosa | California | 95403 | United States |
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| Providence Santa Rosa Memorial Hospital | Recruiting | Santa Rosa | California | 95405 | United States |
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| Saint Joseph's Medical Center | Recruiting | Stockton | California | 95204 | United States |
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| Woodland Memorial Hospital | Recruiting | Woodland | California | 95695 | United States |
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| Penrose-Saint Francis Healthcare | Recruiting | Colorado Springs | Colorado | 80907 | United States |
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| Rocky Mountain Cancer Centers-Penrose | Recruiting | Colorado Springs | Colorado | 80907 | United States |
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| Saint Francis Cancer Center | Recruiting | Colorado Springs | Colorado | 80923 | United States |
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| CommonSpirit Cancer Center Mercy | Recruiting | Durango | Colorado | 81301 | United States |
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| Mercy Medical Center | Recruiting | Durango | Colorado | 81301 | United States |
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| CommonSpirit Saint Anthony Hospital Cancer Center | Recruiting | Lakewood | Colorado | 80228 | United States |
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| Longmont United Hospital | Recruiting | Longmont | Colorado | 80501 | United States |
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| Saint Mary Corwin Medical Center | Recruiting | Pueblo | Colorado | 81004 | United States |
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| Saint Anthony North Hospital | Recruiting | Westminster | Colorado | 80023 | United States |
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| Alfred I duPont Hospital for Children | Recruiting | Wilmington | Delaware | 19803 | United States |
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| Holy Cross Hospital | Recruiting | Fort Lauderdale | Florida | 33308 | United States |
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| Arnold Palmer Hospital for Children | Recruiting | Orlando | Florida | 32806 | United States |
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| Nemours Children's Hospital | Recruiting | Orlando | Florida | 32827 | United States |
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| Nemours Children's Clinic - Pensacola | Recruiting | Pensacola | Florida | 32504 | United States |
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| Augusta University Medical Center | Recruiting | Augusta | Georgia | 30912 | United States |
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| Saint Alphonsus Cancer Care Center-Boise | Recruiting | Boise | Idaho | 83706 | United States |
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| Saint Luke's Cancer Institute - Boise | Recruiting | Boise | Idaho | 83712 | United States |
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| Saint Alphonsus Cancer Care Center-Caldwell | Recruiting | Caldwell | Idaho | 83605 | United States |
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| Kootenai Health - Coeur d'Alene | Recruiting | Coeur d'Alene | Idaho | 83814 | United States |
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| Saint Luke's Cancer Institute - Fruitland | Recruiting | Fruitland | Idaho | 83619 | United States |
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| Idaho Urologic Institute-Meridian | Recruiting | Meridian | Idaho | 83642 | United States |
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| Saint Luke's Cancer Institute - Meridian | Recruiting | Meridian | Idaho | 83642 | United States |
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| Saint Alphonsus Cancer Care Center-Nampa | Recruiting | Nampa | Idaho | 83687 | United States |
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| Saint Luke's Cancer Institute - Nampa | Recruiting | Nampa | Idaho | 83687 | United States |
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| Kootenai Clinic Cancer Services - Post Falls | Recruiting | Post Falls | Idaho | 83854 | United States |
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| Kootenai Clinic Cancer Services - Sandpoint | Recruiting | Sandpoint | Idaho | 83864 | United States |
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| Saint Luke's Cancer Institute - Twin Falls | Recruiting | Twin Falls | Idaho | 83301 | United States |
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| OSF Saint Anthony's Health Center | Recruiting | Alton | Illinois | 62002 | United States |
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| Illinois CancerCare-Bloomington | Recruiting | Bloomington | Illinois | 61704 | United States |
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| Illinois CancerCare-Canton | Recruiting | Canton | Illinois | 61520 | United States |
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| Memorial Hospital of Carbondale | Recruiting | Carbondale | Illinois | 62902 | United States |
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| SIH Cancer Institute | Recruiting | Carterville | Illinois | 62918 | United States |
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| Illinois CancerCare-Carthage | Recruiting | Carthage | Illinois | 62321 | United States |
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| Centralia Oncology Clinic | Recruiting | Centralia | Illinois | 62801 | United States |
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| Saint Mary's Hospital | Suspended | Centralia | Illinois | 62801 | United States |
| Carle at The Riverfront | Recruiting | Danville | Illinois | 61832 | United States |
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| Cancer Care Specialists of Illinois - Decatur | Recruiting | Decatur | Illinois | 62526 | United States |
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| Decatur Memorial Hospital | Recruiting | Decatur | Illinois | 62526 | United States |
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| Illinois CancerCare-Dixon | Recruiting | Dixon | Illinois | 61021 | United States |
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| Carle Physician Group-Effingham | Recruiting | Effingham | Illinois | 62401 | United States |
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| Crossroads Cancer Center | Recruiting | Effingham | Illinois | 62401 | United States |
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| Illinois CancerCare-Eureka | Recruiting | Eureka | Illinois | 61530 | United States |
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| Illinois CancerCare-Galesburg | Recruiting | Galesburg | Illinois | 61401 | United States |
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| Illinois CancerCare-Kewanee Clinic | Recruiting | Kewanee | Illinois | 61443 | United States |
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| Illinois CancerCare-Macomb | Recruiting | Macomb | Illinois | 61455 | United States |
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| Carle Physician Group-Mattoon/Charleston | Recruiting | Mattoon | Illinois | 61938 | United States |
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| SSM Health Good Samaritan | Recruiting | Mount Vernon | Illinois | 62864 | United States |
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| Carle BroMenn Medical Center | Recruiting | Normal | Illinois | 61761 | United States |
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| Carle Cancer Institute Normal | Recruiting | Normal | Illinois | 61761 | United States |
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| Cancer Care Center of O'Fallon | Recruiting | O'Fallon | Illinois | 62269 | United States |
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| HSHS Saint Elizabeth's Hospital | Recruiting | O'Fallon | Illinois | 62269 | United States |
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| Illinois CancerCare-Ottawa Clinic | Recruiting | Ottawa | Illinois | 61350 | United States |
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| Illinois CancerCare-Pekin | Recruiting | Pekin | Illinois | 61554 | United States |
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| Illinois CancerCare-Peoria | Recruiting | Peoria | Illinois | 61615 | United States |
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| Methodist Medical Center of Illinois | Recruiting | Peoria | Illinois | 61636 | United States |
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| Illinois CancerCare-Peru | Recruiting | Peru | Illinois | 61354 | United States |
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| Valley Radiation Oncology | Recruiting | Peru | Illinois | 61354 | United States |
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| Illinois CancerCare-Princeton | Recruiting | Princeton | Illinois | 61356 | United States |
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| Southern Illinois University School of Medicine | Recruiting | Springfield | Illinois | 62702 | United States |
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| Springfield Clinic | Recruiting | Springfield | Illinois | 62702 | United States |
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| Springfield Memorial Hospital | Recruiting | Springfield | Illinois | 62781 | United States |
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| Carle Cancer Center | Recruiting | Urbana | Illinois | 61801 | United States |
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| Illinois CancerCare - Washington | Recruiting | Washington | Illinois | 61571 | United States |
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| UI Health Care Mission Cancer and Blood - Ankeny Clinic | Recruiting | Ankeny | Iowa | 50023 | United States |
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| Saint Anthony Regional Hospital | Recruiting | Carroll | Iowa | 51401 | United States |
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| Mercy Cancer Center-West Lakes | Recruiting | Clive | Iowa | 50325 | United States |
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| UI Health Care Mission Cancer and Blood - West Des Moines Clinic | Recruiting | Clive | Iowa | 50325 | United States |
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| Greater Regional Medical Center | Recruiting | Creston | Iowa | 50801 | United States |
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| Iowa Methodist Medical Center | Recruiting | Des Moines | Iowa | 50309 | United States |
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| UI Health Care Mission Cancer and Blood - Des Moines Clinic | Recruiting | Des Moines | Iowa | 50309 | United States |
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| Broadlawns Medical Center | Recruiting | Des Moines | Iowa | 50314 | United States |
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| Mercy Medical Center - Des Moines | Recruiting | Des Moines | Iowa | 50314 | United States |
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| UI Health Care Mission Cancer and Blood - Laurel Clinic | Recruiting | Des Moines | Iowa | 50314 | United States |
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| UI Healthcare Mission Cancer and Blood - Fort Dodge | Recruiting | Fort Dodge | Iowa | 50501 | United States |
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| UI Healthcare Mission Cancer and Blood - Pella | Recruiting | Pella | Iowa | 50219 | United States |
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| UI Health Care Mission Cancer and Blood - Waukee Clinic | Recruiting | Waukee | Iowa | 50263 | United States |
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| Mercy Medical Center-West Lakes | Recruiting | West Des Moines | Iowa | 50266 | United States |
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| The Iowa Clinic PC | Recruiting | West Des Moines | Iowa | 50266 | United States |
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| Central Care Cancer Center - Garden City | Recruiting | Garden City | Kansas | 67846 | United States |
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| Central Care Cancer Center - Great Bend | Recruiting | Great Bend | Kansas | 67530 | United States |
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| Mercy Hospital Pittsburg | Recruiting | Pittsburg | Kansas | 66762 | United States |
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| CommonSpirit Saint Joseph Hospital - Bardstown | Recruiting | Bardstown | Kentucky | 40004 | United States |
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| Commonwealth Cancer Center-Corbin | Recruiting | Corbin | Kentucky | 40701 | United States |
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| CommonSpirit Saint Joseph Hospital - Lexington | Recruiting | Lexington | Kentucky | 40504 | United States |
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| Saint Joseph Radiation Oncology Resource Center | Recruiting | Lexington | Kentucky | 40504 | United States |
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| CommonSpirit Saint Joseph Medical Center - East Lexington | Recruiting | Lexington | Kentucky | 40509 | United States |
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| CommonSpirit Saint Joseph Hospital London | Recruiting | London | Kentucky | 40741 | United States |
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| CommonSpirit Saint Joseph Hospital Mount Sterling | Recruiting | Mount Sterling | Kentucky | 40353 | United States |
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| MyMichigan Medical Center Gratiot | Recruiting | Alma | Michigan | 48801 | United States |
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| MyMichigan Medical Center Alpena | Recruiting | Alpena | Michigan | 49707 | United States |
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| Trinity Health IHA - Obstetrics and Gynecology West Arbor | Recruiting | Ann Arbor | Michigan | 48103 | United States |
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| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Recruiting | Ann Arbor | Michigan | 48106 | United States |
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| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Recruiting | Brighton | Michigan | 48114 | United States |
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| Trinity Health Medical Center - Brighton | Recruiting | Brighton | Michigan | 48114 | United States |
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| Trinity Health IHA Medical Group Hematology Oncology - Canton | Recruiting | Canton | Michigan | 48188 | United States |
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| Trinity Health Medical Center - Canton | Recruiting | Canton | Michigan | 48188 | United States |
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| Chelsea Hospital | Recruiting | Chelsea | Michigan | 48118 | United States |
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| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Recruiting | Chelsea | Michigan | 48118 | United States |
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| Hematology Oncology Consultants-Clarkston | Recruiting | Clarkston | Michigan | 48346 | United States |
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| Henry Ford Health Saint John Hospital | Recruiting | Detroit | Michigan | 48236 | United States |
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| Henry Ford River District Hospital | Recruiting | East China Township | Michigan | 48054 | United States |
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| OSF Saint Francis Hospital and Medical Group | Recruiting | Escanaba | Michigan | 49829 | United States |
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| Cancer Hematology Centers - Flint | Recruiting | Flint | Michigan | 48503 | United States |
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| Genesee Hematology Oncology PC | Recruiting | Flint | Michigan | 48503 | United States |
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| Genesys Hurley Cancer Institute | Recruiting | Flint | Michigan | 48503 | United States |
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| Hurley Medical Center | Recruiting | Flint | Michigan | 48503 | United States |
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| MyMichigan Medical Center Gladwin | Recruiting | Gladwin | Michigan | 48624 | United States |
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| Henry Ford Saint John Hospital - Academic | Recruiting | Grosse Pointe Woods | Michigan | 48236 | United States |
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| Henry Ford Saint John Hospital - Breast | Recruiting | Grosse Pointe Woods | Michigan | 48236 | United States |
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| Henry Ford Saint John Hospital - Van Elslander | Recruiting | Grosse Pointe Woods | Michigan | 48236 | United States |
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| University of Michigan Health - Sparrow Lansing | Recruiting | Lansing | Michigan | 48912 | United States |
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| Trinity Health Saint Mary Mercy Livonia Hospital | Recruiting | Livonia | Michigan | 48154 | United States |
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| Henry Ford Saint John Hospital - Macomb Medical | Recruiting | Macomb | Michigan | 48044 | United States |
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| Henry Ford Warren Hospital - Breast Macomb | Recruiting | Macomb | Michigan | 48044 | United States |
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| MyMichigan Medical Center Midland | Recruiting | Midland | Michigan | 48670 | United States |
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| MyMichigan Medical Center Mount Pleasant | Recruiting | Mount Pleasant | Michigan | 48858 | United States |
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| Hope Cancer Center | Recruiting | Pontiac | Michigan | 48341 | United States |
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| Michigan Healthcare Professionals Pontiac | Recruiting | Pontiac | Michigan | 48341 | United States |
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| Newland Medical Associates-Pontiac | Recruiting | Pontiac | Michigan | 48341 | United States |
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| Trinity Health Saint Joseph Mercy Oakland Hospital | Recruiting | Pontiac | Michigan | 48341 | United States |
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| MyMichigan Medical Center Saginaw | Recruiting | Saginaw | Michigan | 48601 | United States |
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| MyMichigan Medical Center Tawas | Recruiting | Tawas City | Michigan | 48764 | United States |
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| Henry Ford Health Warren Hospital | Recruiting | Warren | Michigan | 48093 | United States |
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| Henry Ford Madison Heights Hospital - Breast | Recruiting | Warren | Michigan | 48093 | United States |
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| Henry Ford Warren Hospital - GLCMS | Recruiting | Warren | Michigan | 48093 | United States |
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| Huron Gastroenterology PC | Recruiting | Ypsilanti | Michigan | 48106 | United States |
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| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Recruiting | Ypsilanti | Michigan | 48197 | United States |
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| Minnesota Oncology - Burnsville | Recruiting | Burnsville | Minnesota | 55337 | United States |
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| Mercy Hospital | Recruiting | Coon Rapids | Minnesota | 55433 | United States |
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| Fairview Southdale Hospital | Recruiting | Edina | Minnesota | 55435 | United States |
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| Fairview Clinics and Surgery Center Maple Grove | Recruiting | Maple Grove | Minnesota | 55369 | United States |
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| Minnesota Oncology Hematology PA-Maplewood | Recruiting | Maplewood | Minnesota | 55109 | United States |
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| Saint John's Hospital - Healtheast | Recruiting | Maplewood | Minnesota | 55109 | United States |
|
| Abbott-Northwestern Hospital | Recruiting | Minneapolis | Minnesota | 55407 | United States |
|
| Hennepin County Medical Center | Recruiting | Minneapolis | Minnesota | 55415 | United States |
|
| Monticello Cancer Center | Recruiting | Monticello | Minnesota | 55362 | United States |
|
| New Ulm Medical Center | Recruiting | New Ulm | Minnesota | 56073 | United States |
|
| Fairview Northland Medical Center | Recruiting | Princeton | Minnesota | 55371 | United States |
|
| North Memorial Medical Health Center | Recruiting | Robbinsdale | Minnesota | 55422 | United States |
|
| Park Nicollet Clinic - Saint Louis Park | Recruiting | Saint Louis Park | Minnesota | 55416 | United States |
|
| Regions Hospital | Recruiting | Saint Paul | Minnesota | 55101 | United States |
|
| United Hospital | Recruiting | Saint Paul | Minnesota | 55102 | United States |
|
| Saint Francis Regional Medical Center | Recruiting | Shakopee | Minnesota | 55379 | United States |
|
| Lakeview Hospital | Recruiting | Stillwater | Minnesota | 55082 | United States |
|
| Ridgeview Medical Center | Recruiting | Waconia | Minnesota | 55387 | United States |
|
| Rice Memorial Hospital | Recruiting | Willmar | Minnesota | 56201 | United States |
|
| Minnesota Oncology Hematology PA-Woodbury | Recruiting | Woodbury | Minnesota | 55125 | United States |
|
| Fairview Lakes Medical Center | Recruiting | Wyoming | Minnesota | 55092 | United States |
|
| Mercy Oncology and Hematology - Clayton-Clarkson | Recruiting | Ballwin | Missouri | 63011 | United States |
|
| Central Care Cancer Center - Bolivar | Recruiting | Bolivar | Missouri | 65613 | United States |
|
| Cox Cancer Center Branson | Recruiting | Branson | Missouri | 65616 | United States |
|
| Mercy Cancer Center - Cape Girardeau | Recruiting | Cape Girardeau | Missouri | 63703 | United States |
|
| Saint Francis Medical Center | Recruiting | Cape Girardeau | Missouri | 63703 | United States |
|
| Parkland Health Center - Farmington | Recruiting | Farmington | Missouri | 63640 | United States |
|
| Freeman Health System | Recruiting | Joplin | Missouri | 64804 | United States |
|
| Mercy Hospital Joplin | Recruiting | Joplin | Missouri | 64804 | United States |
|
| Lake Regional Hospital | Recruiting | Osage Beach | Missouri | 65065 | United States |
|
| Mercy Clinic-Rolla-Cancer and Hematology | Recruiting | Rolla | Missouri | 65401 | United States |
|
| Phelps Health Delbert Day Cancer Institute | Recruiting | Rolla | Missouri | 65401 | United States |
|
| Heartland Regional Medical Center | Recruiting | Saint Joseph | Missouri | 64506 | United States |
|
| Sainte Genevieve County Memorial Hospital | Recruiting | Sainte Genevieve | Missouri | 63670 | United States |
|
| Mercy Hospital Springfield | Recruiting | Springfield | Missouri | 65804 | United States |
|
| CoxHealth South Hospital | Recruiting | Springfield | Missouri | 65807 | United States |
|
| Mercy Infusion Center - Chippewa | Recruiting | St Louis | Missouri | 63109 | United States |
|
| Mercy Hospital South | Recruiting | St Louis | Missouri | 63128 | United States |
|
| Missouri Baptist Medical Center | Recruiting | St Louis | Missouri | 63131 | United States |
|
| Mercy Hospital Saint Louis | Recruiting | St Louis | Missouri | 63141 | United States |
|
| Missouri Baptist Sullivan Hospital | Recruiting | Sullivan | Missouri | 63080 | United States |
|
| BJC Outpatient Center at Sunset Hills | Recruiting | Sunset Hills | Missouri | 63127 | United States |
|
| Mercy Hospital Washington | Recruiting | Washington | Missouri | 63090 | United States |
|
| Community Hospital of Anaconda | Recruiting | Anaconda | Montana | 59711 | United States |
|
| Billings Clinic Cancer Center | Recruiting | Billings | Montana | 59101 | United States |
|
| Bozeman Health Deaconess Hospital | Recruiting | Bozeman | Montana | 59715 | United States |
|
| Benefis Sletten Cancer Institute | Recruiting | Great Falls | Montana | 59405 | United States |
|
| Great Falls Clinic | Recruiting | Great Falls | Montana | 59405 | United States |
|
| Hi-Line Sletten Cancer Center | Recruiting | Havre | Montana | 59501 | United States |
|
| Benefis Helena Specialty Center | Recruiting | Helena | Montana | 59601 | United States |
|
| Logan Health Medical Center | Recruiting | Kalispell | Montana | 59901 | United States |
|
| Saint Patrick Hospital - Community Hospital | Recruiting | Missoula | Montana | 59802 | United States |
|
| Community Medical Center | Recruiting | Missoula | Montana | 59804 | United States |
|
| CHI Health Saint Francis | Recruiting | Grand Island | Nebraska | 68803 | United States |
|
| CHI Health Good Samaritan | Recruiting | Kearney | Nebraska | 68847 | United States |
|
| Alegent Health Immanuel Medical Center | Recruiting | Omaha | Nebraska | 68122 | United States |
|
| Alegent Health Bergan Mercy Medical Center | Recruiting | Omaha | Nebraska | 68124 | United States |
|
| Alegent Health Lakeside Hospital | Recruiting | Omaha | Nebraska | 68130 | United States |
|
| Novant Health Presbyterian Medical Center | Recruiting | Charlotte | North Carolina | 28204 | United States |
|
| Novant Health Cancer Institute - Huntersville | Recruiting | Huntersville | North Carolina | 28078 | United States |
|
| Novant Health Presbyterian Medical Center Huntersville | Recruiting | Huntersville | North Carolina | 28078 | United States |
|
| Novant Health Cancer Institute - Kernersville | Recruiting | Kernersville | North Carolina | 27284 | United States |
|
| Matthews Radiation Oncology Center | Recruiting | Matthews | North Carolina | 28105 | United States |
|
| Novant Health Cancer Institute - Matthews | Recruiting | Matthews | North Carolina | 28105 | United States |
|
| Novant Health Cancer Institute - Mooresville | Recruiting | Mooresville | North Carolina | 28117 | United States |
|
| Novant Health Cancer Institute - Mount Airy | Recruiting | Mount Airy | North Carolina | 27030 | United States |
|
| Novant Health Cancer Institute - Rowan | Recruiting | Salisbury | North Carolina | 28144 | United States |
|
| Rowan Regional Medical Center | Recruiting | Salisbury | North Carolina | 28144 | United States |
|
| Novant Health Cancer Institute - Thomasville | Recruiting | Thomasville | North Carolina | 27360 | United States |
|
| Novant Health New Hanover Regional Medical Center | Recruiting | Wilmington | North Carolina | 28401 | United States |
|
| Novant Health Forsyth Medical Center | Recruiting | Winston-Salem | North Carolina | 27103 | United States |
|
| Good Samaritan Hospital - Cincinnati | Recruiting | Cincinnati | Ohio | 45220 | United States |
|
| Bethesda North Hospital | Recruiting | Cincinnati | Ohio | 45242 | United States |
|
| TriHealth Cancer Institute-Westside | Recruiting | Cincinnati | Ohio | 45247 | United States |
|
| TriHealth Cancer Institute-Anderson | Recruiting | Cincinnati | Ohio | 45255 | United States |
|
| Mercy Hospital Oklahoma City | Recruiting | Oklahoma City | Oklahoma | 73120 | United States |
|
| Saint Alphonsus Cancer Care Center-Baker City | Recruiting | Baker City | Oregon | 97814 | United States |
|
| Saint Charles Health System | Recruiting | Bend | Oregon | 97701 | United States |
|
| Clackamas Radiation Oncology Center | Recruiting | Clackamas | Oregon | 97015 | United States |
|
| Bay Area Hospital | Recruiting | Coos Bay | Oregon | 97420 | United States |
|
| Providence Hood River Memorial Hospital | Recruiting | Hood River | Oregon | 97031 | United States |
|
| Providence Newberg Medical Center | Recruiting | Newberg | Oregon | 97132 | United States |
|
| Saint Alphonsus Cancer Care Center-Ontario | Recruiting | Ontario | Oregon | 97914 | United States |
|
| Providence Willamette Falls Medical Center | Recruiting | Oregon City | Oregon | 97045 | United States |
|
| Providence Portland Medical Center | Recruiting | Portland | Oregon | 97213 | United States |
|
| Providence Saint Vincent Medical Center | Recruiting | Portland | Oregon | 97225 | United States |
|
| Saint Charles Health System-Redmond | Recruiting | Redmond | Oregon | 97756 | United States |
|
| Lehigh Valley Hospital-Cedar Crest | Recruiting | Allentown | Pennsylvania | 18103 | United States |
|
| Lehigh Valley Hospital - Muhlenberg | Recruiting | Bethlehem | Pennsylvania | 18017 | United States |
|
| Pocono Medical Center | Recruiting | East Stroudsburg | Pennsylvania | 18301 | United States |
|
| Lehigh Valley Hospital-Hazleton | Recruiting | Hazleton | Pennsylvania | 18201 | United States |
|
| Medical University of South Carolina | Recruiting | Charleston | South Carolina | 29425 | United States |
|
| University of Texas Health Science Center at San Antonio | Recruiting | San Antonio | Texas | 78229 | United States |
|
| Bon Secours Memorial Regional Medical Center | Recruiting | Mechanicsville | Virginia | 23116 | United States |
|
| Bon Secours Saint Francis Medical Center | Recruiting | Midlothian | Virginia | 23114 | United States |
|
| Bon Secours Saint Mary's Hospital | Recruiting | Richmond | Virginia | 23226 | United States |
|
| VCU Massey Cancer Center at Stony Point | Recruiting | Richmond | Virginia | 23235 | United States |
|
| VCU Massey Comprehensive Cancer Center | Recruiting | Richmond | Virginia | 23298 | United States |
|
| VCU Community Memorial Health Center | Recruiting | South Hill | Virginia | 23970 | United States |
|
| Providence Regional Cancer System-Aberdeen | Recruiting | Aberdeen | Washington | 98520 | United States |
|
| PeaceHealth Saint Joseph Medical Center | Recruiting | Bellingham | Washington | 98225 | United States |
|
| Providence Regional Cancer System-Centralia | Recruiting | Centralia | Washington | 98531 | United States |
|
| Swedish Cancer Institute-Edmonds | Recruiting | Edmonds | Washington | 98026 | United States |
|
| Providence Regional Cancer Partnership | Recruiting | Everett | Washington | 98201 | United States |
|
| Swedish Cancer Institute-Issaquah | Recruiting | Issaquah | Washington | 98029 | United States |
|
| Kadlec Clinic Hematology and Oncology | Recruiting | Kennewick | Washington | 99336 | United States |
|
| Providence Regional Cancer System-Lacey | Recruiting | Lacey | Washington | 98503 | United States |
|
| PeaceHealth Saint John Medical Center | Recruiting | Longview | Washington | 98632 | United States |
|
| Skagit Regional Health Cancer Care Center | Recruiting | Mount Vernon | Washington | 98274 | United States |
|
| Swedish Medical Center-Ballard Campus | Recruiting | Seattle | Washington | 98107 | United States |
|
| Swedish Medical Center-Cherry Hill | Recruiting | Seattle | Washington | 98122-5711 | United States |
|
| Swedish Medical Center-First Hill | Recruiting | Seattle | Washington | 98122 | United States |
|
| PeaceHealth United General Medical Center | Recruiting | Sedro-Woolley | Washington | 98284 | United States |
|
| Saint Joseph Medical Center Hematology and Oncology - Silverdale | Recruiting | Silverdale | Washington | 98383 | United States |
|
| Cancer Care Northwest - Spokane South | Recruiting | Spokane | Washington | 99202 | United States |
|
| Cancer Care Northwest-Valley | Recruiting | Spokane | Washington | 99216 | United States |
|
| Cancer Care Northwest-North Spokane | Recruiting | Spokane | Washington | 99218 | United States |
|
| PeaceHealth Southwest Medical Center | Recruiting | Vancouver | Washington | 98664 | United States |
|
| Providence Saint Mary Regional Cancer Center | Recruiting | Walla Walla | Washington | 99362 | United States |
|
| Saint Vincent Hospital Cancer Center Green Bay | Recruiting | Green Bay | Wisconsin | 54301 | United States |
|
| Saint Vincent Hospital Cancer Center at Saint Mary's | Recruiting | Green Bay | Wisconsin | 54303 | United States |
|
| Cancer Center of Western Wisconsin | Recruiting | New Richmond | Wisconsin | 54017 | United States |
|
| Saint Vincent Hospital Cancer Center at Oconto Falls | Recruiting | Oconto Falls | Wisconsin | 54154 | United States |
|
| Saint Vincent Hospital Cancer Center at Sheboygan | Recruiting | Sheboygan | Wisconsin | 53081 | United States |
|
| Sheboygan Physicians Group | Recruiting | Sheboygan | Wisconsin | 53081 | United States |
|
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Recruiting | Sturgeon Bay | Wisconsin | 54235-1495 | United States |
|
| Memorial Hospital of Laramie County | Recruiting | Cheyenne | Wyoming | 82001 | United States |
|
| Billings Clinic-Cody | Recruiting | Cody | Wyoming | 82414 | United States |
|
| ID | Term |
|---|---|
| D046248 | Pyloric Stenosis, Hypertrophic |
| ID | Term |
|---|---|
| D011707 | Pyloric Stenosis |
| D017219 | Gastric Outlet Obstruction |
| D013272 | Stomach Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D017216 | Telemedicine |
| D005820 | Genetic Testing |
| D018479 | Early Intervention, Educational |
| D062526 | Patient Navigation |
| D007407 | Interviews as Topic |
| ID | Term |
|---|---|
| D003695 | Delivery of Health Care |
| D010346 | Patient Care Management |
| D006298 | Health Services Administration |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |
| D005821 | Genetic Techniques |
| D033142 | Genetic Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
| D003954 | Diagnostic Services |
| D011314 | Preventive Health Services |
| D002662 | Child Health Services |
| D003153 | Community Health Services |
| D018802 | Patient-Centered Care |
| D011320 | Primary Health Care |
| D003191 | Comprehensive Health Care |
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
Not provided
Not provided