Neurobehavioral Mechanisms of Moral Reasoning: an EEG Stu... | NCT07091409

Studies
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder

NCT07091409

Sponsor

Charite University, Berlin, Germany

Status

Completed

Last Update Posted

Jul 29, 2025Actual

Enrollment

64Actual

Phase

Not provided

Conditions

Borderline Personality Disorder (BPD)

Interventions

Not provided

Countries

Germany

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Oct 2024

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 1, 2024Actual

Primary Completion Date

Jul 20, 2025Actual

Completion Date

Jul 20, 2025Actual

First Submitted Date

Jul 22, 2025

First Submission Date that Met QC Criteria

Jul 22, 2025

First Posted Date

Jul 29, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 22, 2025

Last Update Posted Date

Jul 29, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Katja Wingenfeld, Prof. Dr., Charite University, Berlin, GermanyPrincipal Investigator

Lead Sponsor

Charite University, Berlin, GermanyOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.

Detailed Description

We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations.

We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD.

In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

64Actual

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Number of accidental harm scenarios misclassified as intentional	Accuracy	20 Minutes

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior

Exclusion Criteria:

neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

BPD diagnosis and healthy participants

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Dep. of Psychiatry, CBF		Berlin		12203	Germany

IPD Sharing Statement Module

Plan to Share IPD

Undecided

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D001883	Borderline Personality Disorder

Ancestor Terms

ID	Term
D010554	Personality Disorders
D001523	Mental Disorders

Browse Leaves

Not provided

Browse Branches

Not provided

Label	Type	Description	Intervention Names
Patients with BPD
Healthy individuals