13C-Octanoic Acid Breath Test on Gastric Emptying in Celiac Patients With Functional Disorders

13C-Octanoic Acid Breath Test for the Evaluation of a Low-fodmaps Diet on Gastric Emptying in Celiac Patients With Functional Disorders

The goal of this interventional study is the evaluation of a diet low in fodmaps on gastric emptying in celiac patients with functional disorders.

The goal of this interventional study is the evaluation of a diet low in fodmaps on gastric emptying in celiac patients with functional disorders.

The aims of the study are:

• Evaluation of gastric emptying time by a 13C-Octanoic Acid Breath Test, pre and post-diet (T1 and T2) in celiac patients with functional dyspepsia and non-celiac patients with functional dyspepsia.
• Evaluation of gastrointestinal symptoms, quality of life, and mental health in patients with non-celiac and celiac functional disorders pre- and post-diet (T1 and T2).

Participants:

• Will run the 13C-octanoic acid breath test pre- and post-diet
• Will complete the VAS, SF-36, and SCL-90 questionnaires pre- and post-diet
• Will follow a low fodmap gluten free diet or a regular gluten-free diet for six weeks Researchers will compare celiac and non-celiac patients.

Inclusion Criteria:

• age: ≥ 18 years old
• gender: male or female
• patients who have signed informed consent
• patients diagnosed with a functional gastrointestinal disorder who meet Rome IV criteria (according to Rome Foundation's latest revision of 2016)

Exclusion Criteria:

• patients who have not given informed consent
• patients without a diagnosis of a functional gastrointestinal disorder