Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This randomized controlled trial evaluates the clinical efficacy of a structured early rehabilitation nursing (ERN) pathway compared to routine care in patients with severe acute pancreatitis (SAP). The study aims to determine if the ERN pathway, which includes phased mobility, respiratory training, and psychological support, can improve gastrointestinal recovery, reduce hospital stay and complications, and enhance functional independence and quality of life.
Severe acute pancreatitis (SAP) is a life-threatening condition with high mortality and morbidity, often complicated by prolonged immobilization, leading to muscle atrophy, delayed gut recovery, and increased infection risk. Current nursing practices often neglect early mobilization. This study introduced and tested a structured early rehabilitation nursing pathway (SERNP) designed to address these gaps. A total of 104 eligible SAP patients were randomly assigned to either the SERNP group (n=52) or a control group receiving routine care (n=52). The SERNP intervention was initiated within 48 hours of achieving hemodynamic stability and was delivered in three phases over 14 days: Phase 1 (Days 1-3) focused on bedside passive exercises and respiratory training; Phase 2 (Days 4-7) introduced progressive mobilization like sitting and assisted standing; and Phase 3 (Days 8-14) involved supervised ambulation. The study hypothesis was that the SERNP would accelerate recovery and improve outcomes by addressing both the physiological and psychosocial consequences of SAP.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ERN Group | Experimental | Patients received a structured early rehabilitation nursing pathway (SERNP) in addition to routine care. The intervention was implemented within 48 hours of hemodynamic stability and included:
|
|
| Control Group | Active Comparator | Patients received routine care, which included vital sign monitoring, strict fasting, fluid balance recording, and passive limb mobilization twice daily. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Structured Early Rehabilitation Nursing Pathway | Behavioral | A multi-component, phased nursing intervention focused on early and progressive mobilization, respiratory exercises, and psychological support. |
| Measure | Description | Time Frame |
|---|---|---|
| Time to Relief of Abdominal Distension | Time in days from randomization until the resolution of abdominal distension, as assessed by clinical evaluation. | From randomization up to hospital discharge (an average of 14 days) |
| Time to First Bowel Movement | Time in days from randomization until the first anal exhaust (bowel movement). | From randomization up to hospital discharge (an average of 14 days) |
| Duration of Hospital Stay | Total length of stay in the hospital, measured in days. | From hospital admission up to hospital discharge (an average of 14 days) |
| Incidence of Complications | Percentage of patients who developed complications, including pressure ulcers, pneumonia, and venous thrombosis. | From randomization until hospital discharge (an average of 14 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Activities of Daily Living (ADL) Score | Functional independence measured using the Barthel Index (BI). The scale ranges from 0 to 100, with higher scores indicating greater independence. | Within 24 hours prior to Intensive Care Unit (ICU) discharge |
| Quality of Life (QoL) Score |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Affiliated Hospital of Jianghan University, The Sixth Hospital of Wuhan | Wuhan | Hubei | 430000 | China |
Not provided
| ID | Term |
|---|---|
| D010195 | Pancreatitis |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Routine Care | Behavioral | Standard nursing care for severe acute pancreatitis patients in the ICU, including monitoring and passive limb mobilization. |
|
Quality of life assessed using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire. This measures four domains: physical health, psychological health, social relationships, and environment. Scores are transformed to a 0-100 scale, with higher scores indicating better QoL. |
| At 48 hours prior to hospital discharge |
| Nursing Satisfaction | Patient satisfaction with nursing care, measured using a 10-item Likert scale developed for ICU settings. The rate of patients rating care as "satisfied" or "very satisfied" was calculated. | Within 24 hours prior to hospital discharge |