Neutrophil to Lymphocyte Ratio and Postdural Headache

Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictor of Post-Dural Puncture Headache Following Cesarean Section Under Spinal Anesthesia

This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.

Inclusion Criteria:

• Women aged 18 years or older
• Underwent elective or emergency cesarean section under spinal anesthesia
• Had complete preoperative complete blood count (CBC) data available
• No known hematological or inflammatory disease
• No intraoperative complications recorded
• Medical records accessible for postoperative follow-up regarding PDPH symptoms

Exclusion Criteria:

• Age under 18
• Absence of preoperative complete blood count data
• Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy
• Platelet count <150,000/mm³ or INR >1.5
• Incomplete or missing medical records