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| ID | Type | Description | Link |
|---|---|---|---|
| 1R34DA061051-01A1 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Drug Abuse (NIDA) | NIH |
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This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis. Researchers will gather both interview and survey data from young adults who came to the emergency department after an assault and currently use alcohol or cannabis. Guided by a theory about risky behaviors, the study will focus on how confident young people feel about making changes to their alcohol and cannabis use, and how their friends and family influence their alcohol and cannabis use and involvement in injuries from assault. The team will follow a step-by-step process used by the NIH to adapt and test the improved motivational conversation in the emergency department.
Aim 1: Quantitatively and qualitatively assess self-efficacy, perceived peer and familial norms, and motivation to reduce alcohol and/or cannabis use and engage in treatment referral, among assault-injured emerging adults. AIM 2: Adapt the BNI for use among assault-injured emerging adults with alcohol and/or cannabis misuse in the ED. AIM 3: Determine the feasibility and acceptability of an adapted BNI among assault-injured emerging adults with alcohol and/or cannabis misuse presenting to the ED through a randomized pilot trial comparing those who have received the adapted BNI and treatment referrals to a referrals-only control group. The focus of this registration is the randomized pilot in Aim 3. Anticipated start dates will be reflected in the clinical trial component in Aim 3.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brief Negotiation Interview intervention (BNI) (adapted) | Experimental | Participants randomized to the intervention arm will receive a brief motivational interview designed to increase motivation to reduce alcohol and/or cannabis use and engagement in treatment referral at 30-days. A referral includes a contact number to addiction treatment (primary care and/or specialty addiction care consistent with diagnostic criteria) and injury prevention services at the Yale Hospital Violence Intervention Program. |
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| Control Group | No Intervention | Control group will receive contact referrals only. A referral includes a contact number to addiction treatment (primary care and/or specialty addiction care consistent with diagnostic criteria) and injury prevention services at the Yale Hospital Violence Intervention Program. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brief Negotiation Interview intervention (BNI) (adapted) | Behavioral | A brief motivational interview designed to increase motivation to reduce alcohol and/or cannabis use and engagement in treatment referral. |
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility assessed by recruitment | Recruitment measured as the percentage of those invited/those who enrolled | Day 0 and 30 |
| Feasibility assessed by randomization | Recruitment measured as the percentage of screened eligible participants who enroll/those who receive either intervention or control arm | Day 0 and 30 |
| Feasibility assessed by retention | Recruitment measured as the percentage of those enrolled who have received either intervention or control arm/ participants who have completed all 30-day follow up assessments | Day 0 and 30 |
| Acceptability assessed by Acceptability of Intervention Measure (AIM) | Acceptability of the intervention will be assessed using the Acceptability of Intervention Measure (AIM). It has 4-items scored on a 5-point Likert scale summed to achieve a total score. Total score range of 0-20. Higher scores indicate more acceptability. | Day 0 |
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Inclusion Criteria:
Aim 1:
Aim 2 and 3:
Exclusion Criteria:
Aim 1:
Aim 2 and 3:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Edouard Coupet Jr., MD, MS | Contact | (203) 584-9445 | edouard.coupet@yale.edu |
| Name | Affiliation | Role |
|---|---|---|
| Edouard Coupet, MD, MS | Yale University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yale Department of Emergency Medicine | New Haven | Connecticut | 06520 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41839387 | Derived | Coupet E Jr, Dodington J, D'Onofrio G, Stover CS, Dziura J, Vega CP, Couvertier E, Latham E, Gawel M, Fiellin DA, Fretz SL, Vaca FE. An adapted brief negotiation interview for alcohol and cannabis use among assault-injured emerging adults: A randomized pilot trial protocol. Contemp Clin Trials. 2026 May;164:108287. doi: 10.1016/j.cct.2026.108287. Epub 2026 Mar 14. |
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De-identified individual-level data will be shared 6 months after publication for up to 3 years
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| ID | Term |
|---|---|
| D000064 | Acclimatization |
| ID | Term |
|---|---|
| D000222 | Adaptation, Physiological |
| D010829 | Physiological Phenomena |
| D000220 | Adaptation, Biological |
| D001686 | Biological Phenomena |
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