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Efficacy of Intraoperative pathologic evaluation of central lymph nodes
This study aimed to evaluate the effectiveness of intraoperative pathological examination and determine the risk factors for central lymph node metastasis in patients with unilateral clinically node-negative (cN0) papillary thyroid carcinoma.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| central node dissection | Procedure | dissection of level VI compartment by AAHNS (American association of head and neck surgeons) classification |
| Measure | Description | Time Frame |
|---|---|---|
| the accuracy of IOPE | To evaluate IOPE accuracy, the findings were compared with the final pathology results, utilizing key parameters such as sensitivity, specificity, false-negative rate (FNR), and false-positive rate for analysis. | Perioperative |
| Measure | Description | Time Frame |
|---|---|---|
| the incidence of complications in IOPE [safety of IOPE] | The safety was evaluated by examining the incidence of complications, including vocal cord palsy and hypoparathyroidism. vocal cord palsy : measured by laryngeal sono hypoparathyroidism : serum parathyroid hormone levels < 15.0 pg/mL | up to 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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the patients with unilateral papillary thyroid cancer classified as cN0 and performed with Intraoperative pathologic evaluation
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | Jongno-gu | 03080 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25692116 | Result | Ahn BH, Kim JR, Jeong HC, Lee JS, Chang ES, Kim YH. Predictive factors of central lymph node metastasis in papillary thyroid carcinoma. Ann Surg Treat Res. 2015 Feb;88(2):63-8. doi: 10.4174/astr.2015.88.2.63. Epub 2015 Jan 27. | |
| 37891110 | Result | Bae HL, Ahn JH, Kwak J, Kim HS, Yoon SG, Yi JW, Kim SJ, Lee KE. Intraoperative pathologic evaluation of central compartment lymph nodes in patients undergoing lobectomy for unilateral papillary thyroid carcinoma. Asian J Surg. 2024 Jan;47(1):360-366. doi: 10.1016/j.asjsur.2023.08.203. Epub 2023 Oct 25. |
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| ID | Term |
|---|---|
| D000077273 | Thyroid Cancer, Papillary |
| ID | Term |
|---|---|
| D000231 | Adenocarcinoma, Papillary |
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
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| the risk factors for central lymph node metastasis |
To determine the risk factors for central lymph node metastasis, univariate and multivariate logistic regression analyses were performed to identify the correlations between clinicopathological characteristics and the final pathological presence of central lymph node metastasis. clinicopathological factors : sex, age (<55, ≥55), sonographic features, size (<1cm, ≥1cm) presence of central lymph node metastasis was confirmed by final pathology |
| perioperative |
| D009370 |
| Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D013964 | Thyroid Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D006258 | Head and Neck Neoplasms |
| D004700 | Endocrine System Diseases |
| D013959 | Thyroid Diseases |