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| ID | Type | Description | Link |
|---|---|---|---|
| 400819 | Other Grant/Funding Number | Natural Sciences & Engineering Research Council of Canada |
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The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are:
This study is investigating how the size and presence of almonds (whole vs. chopped) in a white chocolate matrix affect satiation (termination of eating) and postprandial satiety, glycemia, and lipemia. Over three visits, fasted healthy adult female participants will consume three types of white chocolate bark: one with whole almonds, one with chopped almonds, and one with just chocolate. The amount of each ad libitum meal consumed and eating time will be quantified to compare satiation between the confectionery products. Participants will rate their chewing experiences (e.g., exertion, liking, motivations to stop eating) and feelings of satiety up to 180 minutes using paper questionnaires. Participants will also provide finger prick blood samples for determination of glucose and triacylglycerol levels before and after eating each treatment, i.e., at baseline (0 minutes) and 120 (glucose) and 180 (triacylglycerols) minutes after eating. Overall, this study aims to provide insights into the role of food structure in influencing eating and metabolic response and ultimately how food choices can be optimized for better management of blood sugar, satiety, and lipemia to support cardiometabolic health. It is being complemented by a collaboration with researchers in the Department of Food Science at the University of Guelph (led by Prof. Lisa Duizer) examining sensory perception of these same texturally complex foods and the relationship between oral processing behaviour and bolus properties, as well as by in vitro digestion investigations of digestate properties and nutrient release to enable an integrated understanding linking food structure to eating behaviour and postprandial metabolism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| White chocolate with whole almonds | Experimental | Ad libitum serving with 2.25:1 weight per cent chocolate:almonds |
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| White chocolate without almonds | Experimental | Ad libitum serving |
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| White chocolate with chopped almonds | Experimental | Ad libitum serving with 2.25:1 weight per cent chocolate:almonds |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 200 g serving of white chocolate-based confection product | Other | 200 g serving of white chocolate-based confection product |
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| Measure | Description | Time Frame |
|---|---|---|
| Satiation | Weight (g) of chocolate confection consumed during ad libitum meal | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Borg rating of perceived exertion | Paper scale rating of effort required to chew the meal where 0 = No effort at all and 10 = Very very severe chewing effort | Immediately after the ad libitum meal is consumed |
| Eating rate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amanda J Wright, PhD | Contact | 519-824-4120 | 54697 | ajwright@uoguelph.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Human Health Sciences | Recruiting | Guelph | Ontario | N1G 2G4 | Canada |
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Acute meal postprandial study
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Individuals collecting, entering, and analyzing data will be blinded to treatment.
Calculated from time of eating
| Immediately after the ad libitum meal is consumed |
| Blood glucose | Based on finger prick blood analysis | Baseline and 2 hours later |
| Blood triacylglycerols | Based on finger prick blood analysis | Baseline and 3 hours later |
| Postprandial satiety visual analogue scale | Paper questionnaire scale ratings of Hunger, Fullness, Prospective Consumption, and Desire to Eat where each is 100 mm ranging from 0 (minimum) to 100 (maximum). For example, 0 = Not at all Hungry and 100 = As Hungry as Possible. | Baseline until 180 minutes |