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Knee osteoarthritis (KOA) is a chronic, debilitating illness with multiple etiologies that affects the entire knee joint. It is a leading cause of disability among the elderly population and necessitates effective interventions beyond pharmacotherapy due to the associated risks.
This study will address the existing literature gap by focusing on a novel therapeutic approach known as 'Egoscue Exercises', for managing knee osteoarthritis in the affected population.
This Randomized Controlled Trial will be conducted at Riphah Rehab Training and Research Center, Lahore and District Health Quarter Hospital (DHQ), Sahiwal in a time span of 8 months. A sample of 42 participants aged 45-65 years, diagnosed with Grade 02 and 03 Knee Osteoarthritis, will undergo a comprehensive physiotherapy protocol, which includes standard physiotherapy knee OA treatment, either alone or in combination with Egoscue exercises. Participants will receive a minimum of 3 sessions per week, across four weeks.
Randomization, conducted by computer-generated stratified randomization, will ensure unbiased allocation to the two groups. Data collection will be carried out at baseline, 2 weeks, and 4 weeks, and includes outcomes in the form of pain measured by Numeric Pain Rating Scale (NPRS), range of motion measured by Goniometer, and physical function evaluated by Western Ontario and McMaster Universities Arthritis (WOMAC) index. The single-blind study will incorporate rigorous statistical analysis, using IBM SPSS software, version 25 for descriptive statistics, normality, and intergroup differences via t-tests and U tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Egoscue Exercises | Experimental | Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises |
|
| Standard Physical Therapy | Active Comparator | Hot pack & Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard Physical Therapy | Other | Hot pack & Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises |
|
| Measure | Description | Time Frame |
|---|---|---|
| Range of Motion | The range of motion will be measured by using Universal Goniometer, which is a highly reliable and valid tool. It will measure knee joint range of motion which includes knee flexion and extension. | upto 4 weeks |
| Western Ontario and McMaster Universities Arthritis (WOMAC) index | WOMAC Index is widely used in the evaluation of Knee Osteoarthritis. It is a 24 item questionnaire divided into 3 subscales:
| upto 4 weeks |
| Numerical Pain Rating Scale (NPRS) | The Numeric Pain Rating Scale (NPRS) is perhaps the most frequently applied scale used to quantify pain intensity in the clinical setting. It is an 11-point numeric scale, ranging from 0 indicating no pain to 10 indicating worst pain imaginable | upto 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samrood Akram, PhD Scholar | Contact | 03324806143 | samrood.akram@riphah.edu.pk.com |
| Name | Affiliation | Role |
|---|---|---|
| Samrood Akram, PhD* | Riphah International University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Basharat Hospital, Sahiwal | Sahiwal | Punjab Province | 54000 | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33406330 | Background | Sharma L. Osteoarthritis of the Knee. N Engl J Med. 2021 Jan 7;384(1):51-59. doi: 10.1056/NEJMcp1903768. No abstract available. | |
| 34505846 | Background | Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec. |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D010146 | Pain |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| Egoscue Exercises | Other | Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises |
|
| 37047377 | Background | Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update. Int J Mol Sci. 2023 Mar 29;24(7):6405. doi: 10.3390/ijms24076405. |
| Background | Kondal S, Kulkarni V, Gaikwad A, Kharat A, Pant A. Automatic Grading of Knee Osteoarthritis on the Kellgren-Lawrence Scale from Radiographs Using Convolutional Neural Networks [Internet]. arXiv.org. 2020 [cited 2024 Jun 25]. |
| 33207632 | Background | Yunus MHM, Nordin A, Kamal H. Pathophysiological Perspective of Osteoarthritis. Medicina (Kaunas). 2020 Nov 16;56(11):614. doi: 10.3390/medicina56110614. |
| 34784876 | Background | Siddiq MAB, Clegg D, Jansen TL, Rasker JJ. Emerging and New Treatment Options for Knee Osteoarthritis. Curr Rheumatol Rev. 2022;18(1):20-32. doi: 10.2174/1573397117666211116111738. |
| D012216 |
| Rheumatic Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |