Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

The Effect of Ketone Monoester Supplementation and High Altitude on Exercising Cerebral Blood Flow

The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.

Inclusion Criteria:

- Must be a member of the research expedition team travelling to the Barcroft Research Station in White Mountain California

Exclusion Criteria:

• BMI > 30
• No prescribed medications (oral contraceptives excluded)
• History of smoking
• Currently following a ketogenic diet or consuming exogenous ketogenic supplements
• History of heart, lung, blood vessel, or kidney disease
• Currently pregnant