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This study explores the effects of combined aerobic and resistance exercise in patients with non-ischemic dilated cardiomyopathy (NIDCM). In a six-week randomized clinical trial with 66 participants, both exercise groups-combined and aerobic-only-showed significant improvements in exercise capacity, functional independence, dyspnea, and blood pressure. However, no significant difference was found between the two groups. The study concludes that both exercise approaches are effective, but longer studies are needed to determine if combined training offers added benefits.
The study titled "Combined Effect of Aerobic and Resistance Exercise in Non-Ischemic Dilated Cardiomyopathy Patients" by Arooj Fatima investigates how integrating both aerobic and resistance exercises impacts patients suffering from NIDCM, a condition marked by left ventricular dysfunction and reduced exercise tolerance. Through a randomized clinical trial involving 66 patients divided into two groups-one receiving both aerobic and resistance training and the other only aerobic training-the study evaluated changes in ejection fraction, VOâ‚‚ max, dyspnea, and functional independence over six weeks. Significant improvements were observed within both groups across all measured outcomes, including increased exercise capacity, better functional independence, and reduced blood pressure and dyspnea levels. However, no statistically significant difference was found between the two groups, indicating that while both exercise regimens are beneficial, the combined approach did not yield superior results within the study's timeframe. The research highlights the value of structured exercise in improving cardiovascular and functional outcomes in NIDCM patients and recommends longer, more varied studies to further explore these benefits.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Combined Aerobic and Resistance Exercise: | Experimental | Participants performed aerobic training three times a week for six weeks. Each session included a 10-minute warm-up, 30-minute main aerobic activity (60-85% of heart rate reserve using the Karvonen formula), and 10-minute cool-down. Additionally, they performed resistance exercises for upper and lower extremities using TheraBands, 8-10 sets covering major muscle groups, three times a week. |
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| Aerobic Exercise Only | Active Comparator | Participants followed the same aerobic training protocol as Group A. No resistance training was included. Sessions also occurred three times a week for six weeks, with similar warm-up, active, and cool-down phases. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Combined Aerobic and Resistance Exercise | Behavioral | Participants received supervised exercise training 3 times per week for 6 weeks. Each session included a 10-minute warm-up (walking at 1.5 km/h), a 30-minute aerobic phase at 60-85% heart rate reserve (calculated using the Karvonen formula), and a 10-minute cool-down (walking at 1 km/h). In addition, participants performed resistance training for upper and lower extremities using TheraBands, with 8-10 sets targeting major muscle groups. |
| Measure | Description | Time Frame |
|---|---|---|
| Functional Independence Measure (FIM) questionnaire | Assesses level of functional independence across self-care, mobility, communication, and social cognition. | Baseline and 6 weeks |
| VOâ‚‚ Max (Maximum Oxygen Consumption) | Measured using Graded Exercise Test (GXT) to assess cardiovascular fitness. | Baseline and 6 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Modified Borg Dyspnea Scale | Rates severity of dyspnea (shortness of breath) from 0 (none) to 10 (maximum). | Baseline and 6 weeks. |
| Blood Pressure (Systolic and Diastolic) | Measured via Transthoracic Echocardiogram and standard BP monitor. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| imran amjad, phd | Contact | 03324390125 | imran.amjad@riphah.edu.pk |
| Name | Affiliation | Role |
|---|---|---|
| Arjumand Bano, MS-CPPT | Riphah International University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Arjumand | Lahore | Punjab Province | 40100 | Pakistan |
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| ID | Term |
|---|---|
| D009202 | Cardiomyopathies |
| D004417 | Dyspnea |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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| Aerobic Exercise Only | Behavioral | Participants followed the same aerobic training protocol as the experimental group-3 sessions per week for 6 weeks, with 10-minute warm-up, 30-minute aerobic exercise (60-85% HRR), and 10-minute cool-down. No resistance training was provided. |
|
| Baseline and 6 weeks. |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |