Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Dexmedetomidine used as an Additive for Ipack Block in Knee Surgery
Many types of analgesia used but multimodal analgesia showed best results The interspace between the popliteal artery and capsule of the posterior knee (IPACK) block aims to blockade of sciatic nerve terminal branches for analgesia without motor affection
. (IPACK) block is a motor power sparing procedure that involves injecting local anesthetic into the space between the popliteal artery and the posterior capsule of the knee in order to treat posterior knee pain
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bupivacaine | Experimental | IPACK block with 20ml bupivacaine 0.25% alone. . |
|
| Dexmedetomidine | Experimental | IPACK block with 20 ml of bupivacaine 0.25% with dexmedetomidine 100 μg as adjuvant. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine | Drug | dexmedetomidine 100 μg as adjuvant to IPACK block with 20 ml of bupivacaine 0.25%. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale at rest score during first postoperative 48 hours | Visual Analog Scale at rest during first postoperative 48 hours a line 10centimeters long from zero to10 where 10 is the worst pain ever | 48 postoperative hours |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale at rest and during movement at 30 minuts, 2, 8, 16, 24, 36, and 48 hours | Visual Analog Scale at rest during 48 postoperative hour a line 10centimeters long from zero to10 where 10 is the worst pain ever | 48 postoperative hours |
| Duration of the block |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Dalia K Ismail | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of medicine Cairo university | Cairo | Egypt |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Bupivacaine | Drug | 20 ml of bupivacaine 0.25%. |
|
Duration of the block |
| 48 hours |
| Heart Rate | Heart Rate | 48 hours |
| Mean Arterial Pressure | Mean Arterial Pressure | 48 hours |
| Block performance time in minutes | Block performance time in minutes | preoperative |
| Incidence of adverse effects | Incidence of adverse effects | 2 hours inPACU |
| D000813 |
| Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |