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Regional analgesia technique in addition to multimodal analgesia in breast-conserving surgery aims to reduce opioid consumption. This study evaluates the postoperative analgesic efficacy of ultrasound-guided BRILMA block in patients undergoing breast conserving surgery.
Breast-conserving surgery has become a standard surgical approach in the management of early-stage breast malignancies. Despite being less invasive than other oncologic procedures, postoperative pain remains a significant concern. In postoperative pain management, the addition of regional analgesia techniques to multimodal approaches aims to reduce opioid consumption.
First described in 2013, the Serratus-Intercostal Interfascial Plane block targets the branches of the intercostal nerves at the level of the mid-axillary line, specifically around the fourth rib-an anatomical region referred to by the acronym BRILMA. This regional anesthesia technique has demonstrated efficacy in managing postoperative pain, particularly after breast surgery.
In the study, investigators planned to evaluate the postoperative analgesic efficacy of ultrasound-guided BRILMA block via 24-hour morphine consumption in patients undergoing breast conserving surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group B: BRILMA block | Experimental | 20 ml 0.25 % bupivacaine was injected into the fascial plane between the serratus anterior muscle and the external intercostal muscle at T4 level. |
|
| Group C: Control | Other | Standard intravenous analgesia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BRILMA block | Procedure | 20 ml 0.25 % bupivacaine was injected into the fascial plane between the serratus anterior muscle and the external intercostal muscle at T4 level. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Morphine consumption | Amount of morphine consumption | postoperative 24-hour |
| Measure | Description | Time Frame |
|---|---|---|
| Static and dynamic pain scores assessed with numeric rating scale | pain scores recorded at 0., 1., 4., 8., 12., 24. hours postoperatively | postoperative 24 hours |
| number of blocked dermatome | pinprick test in mid-axillary and mid-claviculary line |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nükhet Sivrikoz, Assoc. Prof. Dr. | Attending anesthesiologist | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University, Istanbul Faculty of Medicine | Istanbul | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| Standard intravenous analgesia. | Other | Standard intravenous analgesia. |
|
| 20. minute after block performance |
| Duration of block application | time from the insertion of probe to the removal of needle from skin | up to 15 minutes |
| Amount of fentanyl for sedation. [Time Frame: Intraoperative 2-3 hours] | Amount fentanyl use during surgery | during surgery |
| Rescue analgesia | number of patients needed rescue analgesia | postoperative 24 hours |
| Nausea and vomit | postoperative nausea and vomiting (0=no, 1= mild nausea, 2= severe nausea or vomiting) | postoperative 24 hours |
| Complications | Hematoma, vascular puncture, pneumothorax | Up to 24 hours |
| Patient's satisfaction | Likert scale:1-5 (1: very dissatisfied, 5: very satisfied) | Up to 24 hours |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |