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| ID | Type | Description | Link |
|---|---|---|---|
| J1G-MC-LAKG | Other Identifier | Eli Lilly and Company |
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The main purpose of this study is to evaluate to different formulations of remternetug after single subcutaneous (SC) administration with either an autoinjector (AI) or a prefilled syringe (PFS). The study will look at the amount of remternetug that gets into the bloodstream and how long it takes the body to get rid of the remternetug when given as two different formulations.
Participation in the study will last approximately 155 days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Remternetug (Test) | Experimental | Remternetug administered subcutaneously (SC) via autoinjector (AI) |
|
| Remternetug (Reference) | Experimental | Remternetug administered SC via prefilled syringe. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Remternetug (Test) | Drug | Administered SC |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetic (PK): Maximum Concentration (Cmax) of Remternetug | Predose up to Day 85 | |
| Pharmacokinetic (PK): Area Under the Concentration Versus Time Curve from Zero to time t [AUC(0-t)] of Remternetug | Predose up to Day 85 | |
| Pharmacokinetic (PK): Area Under the Concentration Versus Time Curve from Zero to Infinity [AUC(0-inf)] of Remternetug | Predose up to Day 85 |
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetic (PK): Time of Maximum Concentration (tmax) of Remternetug | Predose up to Day 85 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) | Eli Lilly and Company | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fortrea Clinical Research Unit | Daytona Beach | Florida | 32117 | United States | ||
| QPS Missouri |
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| Remternetug (Reference) | Drug | Administered SC |
|
|
| Springfield |
| Missouri |
| 65802 |
| United States |
| Fortrea Clinical Research Unit | Dallas | Texas | 75247 | United States |