Comparison of the Impact of Different Suspension Mediums on ABO Antibody Titres.

Comparison of the Impact of Different Suspension Mediums on ABO Antibody Titres.

Accurate estimation of ABO antibody titres is vital in Transfusion Medicine due to their involvement in hemolytic transfusion reactions, hemolytic disease of the fetus and newborn, and solid-organ transplant rejection. Although the conventional tube technique (CTT) remains the gold standard, its standardization is challenging, partly influenced by the choice of diluents. This study aimed to compare commonly used diluents in ABO antibody titration via CTT and analyze the resulting titre variations.

Inclusion Criteria:

- Healthy Blood Donor.

Exclusion Criteria:

- Samples from female donors, those with irregular antibodies and reactive to transfusion-transmissible infections on routine testing, were excluded.