Need for ventilation during ICU treatment and, if so, ventilation route (non-invasive and invasive, endotracheal tube and tracheostomy tube) and duration of ventilation

Duration of ventilation during ICU treatment is measured in hours

Oxygenation index/Horowitz index is defined as the ratio of the arterial partial pressure of oxygen (PaO₂, in mmHg) to the fraction of inspired oxygen (FiO₂, expressed as a decimal).

Severity of illness during ICU treatment is assessed with validated intensive care unit scores.

Incidence of delirium in the ICU is measured with validated delirium scores.

Duration of delirium in the ICU is measured in days

Kind of medications required for sedation.

The amount of drug required for sedation.

Duration of sedation is measured in days.

Depth of sedation during ICU treatment

Continuous muscle relaxation during ICU treatment

Vaccination status at the start of ICU treatment

COVID-19-specific immunotherapy (e.g., tocilizumab, dexamethasone, baricitinib) during ICU treatment

Type of anti-infective therapy during ICU treatment

Duration of anti-infective therapy during ICU treatment is measured in days.

Week of pregnancy during ICU treatment in the pregnant women group

Need for a cesarean section in the pregnant women group, yes or no.

Organ complications, including bleeding and pregnancy complications during hospital treatment. Data from patient records.

Nutrition (enteral vs. parenteral) during ICU treatment

Dialysis during ICU treatment (binary)

Dialysis during ICU treatment (duration)

Data from patient records

Data from patient records

Data from patient records

Data from patient records

Participants are followed up for the duration of intensive care unit stay, an expected average of 2 days

Participants are followed up for the duration of hospital stay, an expected average of 7 days

Grip strength at the time of presentation to the PICS outpatient clinic is measured with a dynamometer.

Mobility at the time of presentation to the PICS outpatient clinic is measured with the Timed Up-and-Go (TUG).

Cognition 1 at the time of presentation to the PICS outpatient clinic is measured with the MiniCog. The MiniCog consists of two items, the word recall test and the clock-drawing test. Performance in these test is rated on a scale ranging from 0 - 5, with <3 points indicating a suspicion of dementia.

Cognition 2 at the time of presentation to the PICS outpatient clinic is measured with the Animal Naming Test

Mental health at the time of presentation to the PICS outpatient clinic is measured with Patient Health Questionnaire-4 (It comprises the first two questions of the depression module of the PHQ-D [PHQ-2] and the first two questions of the module for assessing generalized anxiety [GAD-2]) and patient questionnaire with subjective patient assessment.

PBQ at the time of presentation to the PICS outpatient clinic. This questionnaire is a 25-question self-completion questionnaire, which was developed in order to recognize disorders in the mother-child relationship at an early stage.

The questionnaire is made up of 4 scales. Scale 1 Delayed attachment cut-off 12, Scale 2 Rejection and anger cut-off 17, Scale 3 Anxiety cut-off 10 and Scale 4 Risk of child abuse cut-off 3.

The Edinburgh Postnatal Depression Scale (EDPS) was developed to identify women who may have postpartum depression. Each answer is given a score of 0 to 3 .The maximum score is 30. A score of more than 10 suggests minor or major depression may be present.

Health-related quality of life at the time of presentation to the PICS outpatient clinic is measured with EQ-5D-5L questionnaire. Higher Score indicate better Healt-related quality of life.