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| ID | Type | Description | Link |
|---|---|---|---|
| 2024-A02698-39 | Other Identifier | ID RCB |
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Bronchoscopic endoscopy has shown its effectiveness and reliability for the treatment (desobstruction or prothesis) of tumor-induced bronchial obstructions, particularly in the first few weeks. The presence of a lower airway prosthesis can lead to device obstruction requiring daily inhaled fluidification, bacterial colonization, migration of the prosthesis, or the appearance of obstructive or hemorrhagic granulomas.
The aim of this study is to evaluate the quality of life of patients after endobronchial treatment.
It is a prospective, descriptive, and multicentric (national) study. The main objective is to compare the total score on the Saint-George questionnaire at J7 of the interventional endoscopy compared to before the procedure.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bronchoscope | Procedure | procedure performed by bronchoscopy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Saint George Score (quality of life) | Difference between Saint-George score at inclusion and Day 7. The scores for each dimension range from 0 to 100, with a score of 100 indicating excellent health. | At inclusion, and 7 days after therapeutic bronchoscopy |
| Measure | Description | Time Frame |
|---|---|---|
| Saint-George and SF-12 (12-Item Short-Form Health Survey) score | Difference of these scores between inclusion and Day 30 The scores for each dimension of the Saint-George score range from 0 to 100, with a score of 100 indicating excellent health. The SF-12 score ranges from 1 to 60, with a score of 60 indicating very poor quality of life. | at inclusion and Day 30 |
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Inclusion Criteria:
>18 years old
tumoral tracheobronchial obstruction and/or compression
proven solid cancer or suspicion
Acute respiratory distress (at least one of the 5):
Indication for therapeutic interventional endoscopy
No guardianship or curatorship
Non-hematological tumor
Exclusion Criteria:
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Inclusion Criteria:
>18 years old
tumoral tracheobronchial obstruction and/or compression
proven solid cancer or suspicion
Acute respiratory distress (at least one of the 5):
Indication for therapeutic interventional endoscopy
No guardianship or curatorship
Non-hematological tumor
Exclusion Criteria:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anne-Claire Toffart, MD-PhD | Contact | +33476766831 | atoffart@chu-grenoble.fr |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38391185 | Background | Roy P, Fournier C, Barnestein R, Wallyn F, Bourinet V, Briault A, Camuset J, Cellerin L, Crutu A, Dewolf M, Egenod T, Favrolt N, Heluain V, Lorut C, Mangiapan G, Schlossmasscher P, Toublanc B, Usturoi D, Legodec J, Vergnon JM, Pajiep Chapda MC, Dutau H, Guibert N. Outcomes of Therapeutic Bronchoscopy in Malignant Airway Obstruction Causing Acute Respiratory Failure. Ann Am Thorac Soc. 2024 May;21(5):833-837. doi: 10.1513/AnnalsATS.202311-943RL. No abstract available. | |
| 40188807 |
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| ECOG-performance Status | It ranges from 0 (fully active) to 5 (dead). | inclusion and Day 30 |
| Duration of ventilatory support (mechanical ventilation, non-invasive ventilation, high-flow oxygen) | During the 30 first days from intervention |
| hospitalization duration | During the 30 first days from intervention |
| anti-tumoral treatment | initiation or continuation of anti-tumour treatment (radiotherapy, chemotherapy, immunotherapy, targeted therapy) | During the 30 first days from intervention |
| survival | through study completion, an average of 1 year |
| Background |
| Roy P, Roy P, Amari L, Laroumagne S, Legodec J, Fournier C, Cellerin L, Lorut C, Gonin F, Vergnon JM, Egenod T, Favrolt N, Schlossmacher P, Bourinet V, Perrot L, Lachkar S, Camuset J, Briault A, Degot T, Gut-Gobert C, Mangiapan G, Jasnot JY, Briens E, Crutu A, Marceau A, Toublanc B, Dewolf M, Dutilh J, Germain N, Tronchetti J, Astoul P, Guibert N, Dutau H. Predictive Factors of Clinical Success of Therapeutic Bronchoscopy in Malignant Central Airway Obstruction: Results from the EpiGETIF Registry. Respiration. 2025;104(9):667-677. doi: 10.1159/000545568. Epub 2025 Apr 4. |
| ID | Term |
|---|---|
| D020680 | Bronchoscopes |
| ID | Term |
|---|---|
| D019723 | Endoscopes |
| D019719 | Diagnostic Equipment |
| D004864 | Equipment and Supplies |
| D013523 | Surgical Equipment |
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