Analysis of Cerebrospinal Fluid in Patients With Cerebral... | NCT07044037

Studies
Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)

NCT07044037

Sponsor

Centre Hospitalier de Saint-Denis

Status

Completed

Last Update Posted

Jun 29, 2025Actual

Enrollment

53Actual

Phase

Not provided

Conditions

Toxoplasmosis, Cerebral
Toxoplasmosis
Meningitis
HIV Infections
Cerebrospinal Fluid
Central Nervous System Infections

Interventions

Not provided

Countries

France

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jun 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jul 1, 2024Actual

Primary Completion Date

Dec 31, 2024Actual

Completion Date

Dec 31, 2024Actual

First Submitted Date

Jun 12, 2025

First Submission Date that Met QC Criteria

Jun 23, 2025

First Posted Date

Jun 29, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 23, 2025

Last Update Posted Date

Jun 29, 2025Actual

Description Module

Brief Summary

This study looks at patients who were treated for cerebral toxoplasmosis at CHSD between 2004 and 2024. It focuses on analyzing their cerebrospinal fluid (CSF) to better understand the biological signs of the disease. The goal is to see if CSF results can show signs of meningitis, even though it's not commonly reported, and to describe any co-infections, symptoms, brain imaging findings, and patient outcomes.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

53Actual

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Number of participants with treatment-related adverse events as assessed by CTCAE v4.0		From hospital admission to completion of diagnostic lumbar puncture and initial treatment (typically within the first 7 days of hospitalization).

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

- Adult patients (age 18 years) hospitalized at CHSD between January 1, 2004 and March 31, 2024 for cerebral toxoplasmosis

Exclusion Criteria:

- Under 18 years ols

Accepts Healthy Volunteers

Not provided

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

The study population includes adult patients (aged 18 years and older) who were hospitalized at the Centre Hospitalier de Saint-Denis (CHSD) between January 1, 2004, and March 31, 2024, with a principal or significant associated diagnosis of cerebral toxoplasmosis.

Sampling Method

Non-Probability Sample

Facility	Status	City	State	ZIP	Country	Contacts
France		Saint-Denis	France		France

Condition Browse Module

MeSH Terms

ID	Term
D016781	Toxoplasmosis, Cerebral
D014123	Toxoplasmosis
D008581	Meningitis
D015658	HIV Infections
D002494	Central Nervous System Infections

Ancestor Terms

ID	Term
D001922	Brain Abscess
D007239	Infections
D020808	Central Nervous System Protozoal Infections
D020807	Central Nervous System Parasitic Infections

Browse Leaves

Not provided

Browse Branches

Not provided