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The goal of this prospective cohort study is to investigate the relationship between the TyG index and early identification of MVO in AMI patients undergoing emergency PCI and CMR imaging. The study will enroll approximately 300 AMI patients treated at Xiangya Third Hospital of Central South University from June 2024 to August 2025. The main questions it aims to answer are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High TYG Index Group | |||
| Medium TYG Index Group | |||
| Low TYG Index Group |
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| Measure | Description | Time Frame |
|---|---|---|
| The presence or absence of microvascular obstruction (MVO) diagnosed by cardiac magnetic resonance (CMR) within 3-7 days postoperatively | 3-7 days postoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with acute myocardial infarction
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| can Zhu Can | Contact | +8613348674820 | zhucan1021@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xiangya Third Hospital of Central South University | Recruiting | Changsha | Hunan Province,China | 410013 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28830471 | Result | Kim MK, Ahn CW, Kang S, Nam JS, Kim KR, Park JS. Relationship between the triglyceride glucose index and coronary artery calcification in Korean adults. Cardiovasc Diabetol. 2017 Aug 23;16(1):108. doi: 10.1186/s12933-017-0589-4. | |
| 26800769 | Result | Soeda T, Higuma T, Abe N, Yamada M, Yokoyama H, Shibutani S, Ong DS, Vergallo R, Minami Y, Lee H, Okumura K, Jang IK. Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture. Eur Heart J Cardiovasc Imaging. 2017 Jan;18(1):103-110. doi: 10.1093/ehjci/jev341. Epub 2016 Jan 22. |
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The nature of the data collected in this study includes sensitive information that is closely tied to the identity of the participants. Out of respect for the privacy and confidentiality of our participants, and in strict adherence to the terms of the informed consent they provided, we are unable to share individual participant data. We believe that protecting the privacy of our participants is of utmost importance, and we are committed to upholding these ethical standards throughout our research.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Feb 27, 2025 | Jun 14, 2025 | Prot_SAP_000.pdf |
| ICF | No | No | Yes | Informed Consent Form: Informed Consent Form | Mar 1, 2025 | May 28, 2025 | ICF_001.pdf |
| ICF | No | No | Yes | Informed Consent Form: Ethical approval document | Mar 1, 2025 | May 28, 2025 | ICF_002.pdf |
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| 16182882 | Result | Alberti KG, Zimmet P, Shaw J; IDF Epidemiology Task Force Consensus Group. The metabolic syndrome--a new worldwide definition. Lancet. 2005 Sep 24-30;366(9491):1059-62. doi: 10.1016/S0140-6736(05)67402-8. No abstract available. |