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This study aimed to evaluate the impact of fortified biscuit consumption on the iron status of school-aged children in rural Kaolack.
The main question it aims to answer is:
• Does the consumption of iron-fortified biscuits improve the iron status of school-aged children? Researchers compared the iron-fortified biscuit to a placebo (a biscuit similar in appearance but without iron-rich ingredients) to measure its effectiveness.
Participants:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental group | Experimental | This group included 286 school-aged children (6-16 years) enrolled in a French public elementary school in Keur Socé. |
|
| Control group | Placebo Comparator | This group consisted of 210 children (aged 6-16 years) from a Franco-Arabic elementary school in the same locality. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fortified Biscuit with Local Iron-Rich Ingredients | Dietary Supplement | Participants consumed one fortified biscuit per day, five days a week (school days), for a period of three months. The biscuit was formulated using wheat flour, millet, maize, peanut paste, sugar, and was filled with a blend of Moringa oleifera, Hibiscus sabdariffa, Adansonia digitata, and Detarium senegalense-all selected for their high iron and vitamin C content. The iron content was approximately 4 mg per 100 g. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in serum ferritin concentration (ng/mL) | At baseline and at 3 months (endline) | |
| Prevalence of iron deficiency | At baseline and at 3 months (endline) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in hemoglobin concentration (g/dL) | At baseline and at 3 months (endline) | |
| Prevalence of anemia (mild, moderate, severe) | At baseline and at 3 months (endline | |
| Measure | Description | Time Frame |
|---|---|---|
| Sex (male/female) | at baseline | |
| Age of participants | At baseline and at 3 months (endline) |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| École Élémentaire de Keur Socé City: Kaolack Country: Senegal | Kaolack | Senegal |
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Participants were randomly assigned to one of two parallel groups: an intervention group receiving iron-fortified biscuits and a control group receiving placebo biscuits with similar appearance but without iron-rich ingredients. The intervention lasted for 3 months, and outcomes were assessed before and after the intervention period.
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In this study, both participants and data collectors were blinded to the group assignments. Participants were unaware whether they were receiving the iron-fortified biscuit or the placebo biscuit, as both were similar in appearance and taste. Additionally, data collectors responsible for anthropometric and biological measurements were not informed of the participants' allocation to ensure objectivity in data collection. However, the study coordinators and investigators were aware of the intervention allocation due to the nature of the study design.
|
| Non-Fortified Biscuit | Dietary Supplement | Participants received a placebo biscuit daily for the same period and frequency as the intervention group. The placebo biscuit was visually and texturally identical to the fortified biscuit but did not contain the micronutrient-rich filling. |
|
| Change in BMI-for-age Z-score (BMIZ-WHO) |
| At baseline and at 3 months (endline |
| prevalence of thinness (BMIZ < -2 SD) | At baseline and at 3 months (endline) |
| C-reactive protein (CRP) concentration | At baseline and at 3 months (endline) |
| Alpha-1-acid glycoprotein (AGP) concentration | At baseline and at 3 months (endline) |
| ID | Term |
|---|---|
| D000740 | Anemia |
| ID | Term |
|---|---|
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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