Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis

Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis

This study aims to reveal the immune and inflammatory regulatory molecular mechanisms related to the progression of allergic bronchopulmonary aspergillosis (ABPA), and to build a precision typing based on inflammation and identify the biomarkers of typing, and to explore the clinical outcomes of different inflammatory phenotypes.

Inclusion Criteria:

• Meets the diagnostic criteria for allergic bronchopulmonary aspergillosis.
• Meets the diagnostic criteria for fungal-sensitized asthma.

Exclusion Criteria:

• Human immunodeficiency virus infection.
• Malignant tumor.
• Blood system disease.
• autoimmune system disease.
• History of pulmonary tuberculosis.
• Patients with a history of smoking or still smoking.
• Invasive pulmonary fungal disease.
• Contraindications electronic bronchoscopy