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This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia. Immune-nutritional scores, including the Prognostic Nutritional Index (PNI) and Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, will be calculated using routine preoperative blood parameters. Postoperative sleep quality will be assessed using the Richards-Campbell Sleep Questionnaire (RCSQ). Secondary outcomes include postoperative pain scores and patient satisfaction. The study will enroll 60 patients and seeks to determine whether preoperative physiological markers can predict subjective recovery parameters such as sleep and comfort, potentially contributing to personalized perioperative care.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immune-Nutritional Scoring and Postoperative Sleep Assessment | Other | Routine preoperative laboratory data (hemoglobin, albumin, lymphocyte, platelet) will be used to calculate immune-nutritional scores (HALP, PNI). Postoperative sleep quality will be assessed with the Richards-Campbell Sleep Questionnaire (RCSQ). |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Sleep Quality Score | Sleep quality will be measured using the Richards-Campbell Sleep Questionnaire (RCSQ), a validated 5-item instrument assessing sleep depth, latency, number of awakenings, efficiency, and overall quality. Each item is scored from 0 to 100, with higher scores indicating better sleep quality. | Postoperative first night |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain Score | Pain levels will be assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst pain imaginable). Scores will be recorded at rest and during mobilization on each postoperative day. | Post-anesthesia care unit (PACU), postoperative day 1 and day 2 (rest and mobilization) |
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Inclusion Criteria:
Exclusion Criteria:
Female participants only. The study population includes women aged 18 to 70 undergoing elective total abdominal hysterectomy under general anesthesia.
The study population consists of female patients aged 18 to 70 years undergoing elective total abdominal hysterectomy under general anesthesia at Haseki Training and Research Hospital. Participants must have available preoperative laboratory data and be able to complete postoperative questionnaires.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| ilke dolgun | Contact | +905555485632 | ilkeser2004@gmail.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21960370 | Result | Li J, Guo Q, Ye X, Lin J, Yi C, Mao H, Yang X, Yu X. Prevalence and risk factors of sleep disturbance in continuous ambulatory peritoneal dialysis patients in Guangzhou, southern China. Int Urol Nephrol. 2012 Jun;44(3):929-36. doi: 10.1007/s11255-011-0060-5. Epub 2011 Sep 30. | |
| 37103068 | Result | Ishiguro T, Aoyama T, Ju M, Kazama K, Fukuda M, Kanai H, Sawazaki S, Tamagawa H, Tamagawa A, Cho H, Hara K, Numata M, Hashimoto I, Maezawa Y, Segami K, Oshima T, Saito A, Yukawa N, Rino Y. Prognostic Nutritional Index as a Predictor of Prognosis in Postoperative Patients With Gastric Cancer. In Vivo. 2023 May-Jun;37(3):1290-1296. doi: 10.21873/invivo.13207. |
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| Patient Satisfaction Score |
Overall patient satisfaction with the perioperative experience will be assessed using a 0-10 numeric rating scale, with higher scores indicating greater satisfaction. |
| Postoperative day 2 |
| 36848404 | Result | Farag CM, Antar R, Akosman S, Ng M, Whalen MJ. What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types. Oncotarget. 2023 Feb 25;14:153-172. doi: 10.18632/oncotarget.28367. |
| Result | Para E, Uslu N. Cerrahi hastalarında ameliyat sonrası uyku kalitesi ve uyku düzenini etkileyen etmenler. CBU Sağlık Bilimleri Dergisi. 2022;9(3):443-450. doi:10.34087/cbusbed.1034063. |