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| Name | Class |
|---|---|
| Geriatrics Research Institute of Henan Provincial People's Hospital | UNKNOWN |
| Beijing Institute of Heart, Lung and Blood Vessel Diseases | OTHER |
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With the continuous development of China's economy and the improvement of medical standards, the life expectancy of the Chinese population has significantly increased. Against the backdrop of accelerating aging in China, the incidence of age-related chronic non-communicable diseases (NCDs), such as cardiovascular and cerebrovascular diseases and chronic respiratory diseases, has risen remarkably. These diseases are characterized by multiple comorbidities, high disability rates, and high mortality rates, severely compromising the quality of life of older adults, exacerbating family burdens, and straining healthcare systems. This constitutes one of the major challenges faced by aging societies. Therefore, early detection and intervention of chronic diseases in older adults are critical measures to address population aging.
Comprehensive geriatric assessment (CGA), a core specialty of geriatric medicine, serves as a fundamental framework for the clinical identification of geriatric syndromes and multidisciplinary management. It is emerging as a key pathway to promote "healthy aging." Guided by this premise, this study aims to explore the application value of CGA in managing chronic diseases among older adults, with the goal of achieving full-cycle management for early detection, diagnosis, and treatment of chronic conditions in China's elderly population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elderly patients with chronic diseases | The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on. We compared various biochemical indexes, cardiac function indexes, quality of life, and the occurrence of long-term adverse events before and after the comprehensive geriatric assessment and management. |
| |
| Healthy elderly population | The control group was composed of elderly subjects without evidence of chronic diseases. Chronic diseases was excluded by performing a complete medical history, a comprehensive physical examination, and an echocardiogram. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| comprehensive geriatric assessment | Diagnostic Test | The comprehensive geriatric assessment (CGA) is a multi dimensional diagnostic process used to determine the medi cal, psychological, and functional capabilities of a frail elderly person to develop a coordinated and integrated plan for treat ment and long-term follow-up. |
| Measure | Description | Time Frame |
|---|---|---|
| Major adverse events (MAE) | Major adverse events (MAE) in overall population, defined as composite of all-cause death, Heart Failure hospitalization, recurrent myocardial infarction, stroke, etc. | These data is collected during follow-up visit at 3/6/12/24/36 months after discharge |
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| Measure | Description | Time Frame |
|---|---|---|
| Age for each participant | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting | |
| Gender for each participant | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
Inclusion Criteria:
Exclusion Criteria:
1. Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language, psychiatric disturbances).
2. Presence of serious/severe co-morbidities in the opinion of the investigator which may limit short term (i.e. 6 month) life expectancy.
3. Current participation in a randomised interventional clinical trial.
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The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yang Xinying Yang Xinying | Contact | 0371-87160164 | xinyingyang150@163.com |
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| Height for each participant | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Weight for each participant | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Contact information for each participant | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Past Medical History including disease history, surgical history, and family medical history | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Lifestyle including smoking history and drinking, specify how many years smoking or drinking lasted and detail quantity per day | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：blood lipid | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：blood glucose | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：uric acid | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：urea | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：creatinine | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：C reactive protein | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：D-dimer | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| blood biochemical index：NT-proBNP | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Cardiac ultrasound | The whole results of echocardiography report will be recorded. The indicates which can reflect cardiac function including Left ventricular ejection fraction, left ventricular end diastolic diameter, E/A ratio of bicuspid valve will be used to calculate the association with metabolites. | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Drug treatment | Oral drug therapy, including antiplatelet drugs, antihypertensive drugs, lipid-lowering drugs, etc. | These data is collected from the cases' medical record in an average of 1 month after the sample recruiting |
| Comprehensive Geriatric Assessment: Frailty | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Sarcopenia | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Falls | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Disability | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Dysphagia | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Malnutrition | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Urinary incontinence | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Fecal incontinence | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Constipation | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Cognitive impairment | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Anxiety state | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Depressive state | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Sleep disorders | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Pain | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Social support | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |
| Comprehensive Geriatric Assessment: Home environment | These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment |