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The objective of this study is to evaluate the pharmacokinetics and pharmacodynamics of SHR-3167 at steady state in subjects with type 2 diabetes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SHR-3167 Group | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SHR-3167 Injection | Drug | SHR-3167 injection. |
| |
| Insulin Degludec Injection |
| Measure | Description | Time Frame |
|---|---|---|
| Area under the SHR-3167 concentration-time curve (AUC SHR-3167, tau, ss). | From 0 to 168 hours after SHR-3167 administration. |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum observed SHR-3167 concentration (Cmax, ss). | From 0 to 168 hours after SHR-3167 administration. | |
| Adverse events (AEs). | 21 weeks to 43 weeks. | |
| Hypoglycemic events. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Han Jianting | Contact | +86-0518-82342973 | jianting.han.jh27@hengrui.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Hospital of Sichuan University | Recruiting | Chengdu | Sichuan | 200433 | China |
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| Drug |
Insulin Degludec injection. |
|
| 21 weeks to 43 weeks. |
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| C571886 | insulin degludec |
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