Association of Genetic Variants With Myopia

Genetic Variants and Their Association With Myopia Risk, Progression, and Optimal Interventions in Children

This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length). It will also examine how different treatments-such as low-dose atropine drops, orthokeratology lenses, specialized glasses, and increased outdoor time-interact with these genes. Finally, the research will develop a genetic risk score to help tailor personalized myopia prevention and treatment plans.

Inclusion Criteria:

• Age 6-18 years.
• Any Spherical equivalent refraction (SER)
• Parental consent for genetic testing.

Exclusion Criteria:

• Suspected genetic syndromes (e.g., Stickler, Marfan).
• Other eye diseases (e.g., glaucoma, cataracts, retinal abnormalities, strabismus).
• Prior refractive surgery