Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

Physical Prehabilitation With and Without Creatine/Whey Protein Supplementation Effects on Frailty In Patients With Cirrhosis

Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.

Inclusion Criteria:

• Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography
• Access to digital device and internet at home
• Ability to provide written informed consent before any study-related activities
• Ability to remain in study for at least 3 months

Exclusion Criteria:

• Allergy to milk protein
• On hemodialysis
• No English language proficiency
• Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data
• Concomitant severe underlying systemic illness that in the opinion of the Investigator would interfere with completion of study
• Pregnant, breastfeeding, or intention of becoming pregnant during study time frame