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| ID | Type | Description | Link |
|---|---|---|---|
| ID RCB : 2021-A01115-36 | Other Identifier | ANSM |
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Short stature is defined as a height less than -2 Standard Deviations (SD) for age and a slowing of growth velocity by a loss of 1 SD/year. The causes of short stature are multiple (chronic diseases, growth hormone deficiency, hypothyroidism, hyperadrenocorticism, genetic syndromes, etc.). However, nearly 30% are considered idiopathic, with no identified etiology (Naccache et al., unpublished).
Growth hormone (GH) is secreted in a pulsatile manner with maximum peaks primarily at night, raising questions about the relationship between sleep disturbances and short stature.
In children, one of the main causes of sleep disturbances in the digital age is screen use, which is becoming increasingly important, particularly in the pediatric population.
During the night, physiologically, the retina, which no longer receives light signals, sends a message to the suprachiasmatic nucleus, the main key element of the internal clock, and to the pineal gland, which synthesizes melatonin, the sleep hormone. Exposing screens to blue light therefore disrupts melatonin secretion, which leads to a disruption of the circadian rhythm and therefore sleep. Note that this effect of light on melatonin secretion depends on the time of day of exposure, the intensity, and the duration. Thus, exposure to screens before bedtime can be responsible for a delay or even an absence of melatonin synthesis, particularly in the case of nighttime awakenings.
While many studies have examined the impact of screens on children's psychological balance, weight, etc., none, to our knowledge, has examined the potential impact of screens on children's height growth. Hypothesis of this project: 70% of GH synthesis takes place at night, a few minutes after entering slow-wave sleep, sleep disturbed by screens could mean a lower secretion of GH and consequently a delay in height growth.
The objective of this project is to evaluate the impact of screen consumption on sleep and the impact of sleep on idiopathic growth disorder.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Growth hormone stimulation test group |
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| Measure | Description | Time Frame |
|---|---|---|
| Screen consumption on sleep | Evaluation of the Impact of Screen Consumption on Sleep by Answers to the Questionnaire Given to the Child and/or Parent(s) (Depending on Age) | At enrollment visit |
| Screen consumption on sleep | Sleep assessment by responses to the questionnaire given to the child and/or the parent(s) (depending on age) in order to assess the duration of sleep | At enrollment visit |
| Screen consumption on sleep | Evaluation of the Impact of Screen Consumption on Sleep by Answers to the Questionnaire Given to the Child and/or Parent(s) (Depending on Age) in Order to Evaluate child's physical activity | At enrollment visit |
| Impact of sleep on idiopathic growth disorder | Collection of auxological data at the time of the day hospital consultation (height) noted in the health record and/or in the hospital medical file | At enrollment visit |
| Impact of sleep on idiopathic growth disorder | Collection of auxological data at the time of the day hospital consultation (weight) noted in the health record and/or in the hospital medical file | At enrollment visit |
| Impact of sleep on idiopathic growth disorder | Collection of auxological data at the time of the day hospital consultation (age) noted in the health record and/or in the hospital medical file | At enrollment visit |
| Measure | Description | Time Frame |
|---|---|---|
| Impact of screens on body size (BMI) | Evaluation of the impact of screens on body size (BMI) by response to the questionnaire given to the child and/or the parent(s) | At enrollment visit |
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Inclusion Criteria:
Exclusion Criteria:
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Any patient coming to the day hospital for a growth hormone stimulation test and/or for an oral provocation test in the context of an allergy,
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| Name | Affiliation | Role |
|---|---|---|
| Mireille MC CASTANET, Professor | University Hospital, Rouen | Principal Investigator |
| Mireille MC CASTANET, Professor | University Hospital, Rouen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital of Rouen | Rouen | 76031 | France |
The data provided will be the property of the sponsor and will be used solely for its own research activities.
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| ID | Term |
|---|---|
| D006130 | Growth Disorders |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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