A Study to Assess the Tolerability and Safety of Subcutaneously (SC) Administered Immunoglobulin G (IgG) With Varying Injection Conditions

A Phase 1, Open-Label, Fixed-Sequence, Randomized Study to Assess the Tolerability and Safety of Subcutaneously Administered Immunoglobulin G With Varying Injection Conditions

This study will evaluate the safety and tolerability of SC administration of IgG in healthy participants.

Inclusion Criteria:

• Body mass index (BMI) 18 to 36 kilograms per meter square (kg/m^2), inclusive
• For females of childbearing potential: agreement to remain abstinent (refrain from heterosexual intercourse) or use adequate contraception during IgG administration and for 28 days after completion of IgG administration
• For males: agreement to remain abstinent (refrain from heterosexual intercourse) or use a condom, and agreement to refrain from donating sperm

Exclusion Criteria:

• Pregnancy or breastfeeding, or intention of becoming pregnant during the study or within 28 days after the last study drug administration
• Positive human immunodeficiency virus (HIV) test
• Positive hepatitis B surface antigen or hepatitis B core antibody test
• Positive hepatitis C virus antibody test
• Regular alcohol consumption of >8 drinks/week for females or >12 drinks/week for males
• Poor peripheral venous access
• Major surgical procedure within 28 days prior to initiation of study treatment or anticipation of need for a major surgical procedure during the study
• Known hypersensitivity to IgG or any of its components or to products made with IgG
• History or presence of skin rash or other skin disorders
• Inability to sense pain (e.g., peripheral neuropathy) or have a history of or have been diagnosed with a chronic pain syndrome
• Infection or inflammation of the designated injection site (abdomen)