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This randomized controlled trial (RCT) compares the analgesic effectiveness of two regional anesthesia techniques-Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve Block (LFCB) versus Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB and S-ESPB)-in pediatric patients undergoing hip surgery.
Orthopedic hip procedures in pediatric patients, including osteotomies, arthroscopic interventions, and reconstructive surgeries, often result in significant postoperative pain. Effective analgesia is critical for reducing surgical stress, accelerating rehabilitation, and minimizing opioid use and associated side effects. Regional anesthesia techniques have gained attention for their opioid-sparing effects and enhanced recovery profiles.
This randomized controlled trial aims to compare the analgesic effectiveness of two regional anesthetic approaches:
- The pericapsular nerve group (PENG) block is combined with the lateral fetal cutaneous nerve block (LFCB), targeting hip joint innervation directly and providing comprehensive sensory coverage.
Lumbar and sacral erector spinae plane blocks (L-ESPB and S-ESPB) employ fascial plane techniques to deliver analgesia by diffusing local anesthetic around nerves innervating the hip region.
This trial aims to establish the optimal regional anesthesia technique and determine the clinical benefits of using dexamethasone and dexmedetomidine as adjuvants. The results will guide clinicians toward evidence-based analgesic protocols in pediatric orthopedic hip surgery, potentially reducing opioid-related complications and improving patient recovery outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PENG + LFCB | Active Comparator | U-S guided PENG block - 0.4ml/kg 0.2% ropivacaine + U-S guided LFCB - 0.1ml/kg 0.2% ropivacaine |
|
| L-ESPB + S-ESPB | Active Comparator | U-S guided L-ESPB - 0.25ml/kg 0.2% ropivacaine + U-S guided S-ESPB - 0.25ml/kg 0.2% ropivacaine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ropivacaine 0.2% for PENG Block | Drug | U-S guided PENG (0.4 mL/kg) with 0.2% ropivacaine |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Total Opioid Consumption | Total opiate consumption after surgery | 48 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Time to first rescue opioid analgesia | Time after surgery when the patient needs opiate for the first time | 48 hours after surgery |
| Numerical Rating Scale [range 0:10] | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Malgorzata Reysner | Contact | +48 61 873 83 03 | mreysner@ump.edu.pl |
| Name | Affiliation | Role |
|---|---|---|
| Malgorzata Reysner, M.D. Ph.D. | Poznan University of Medical Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Poznan University of Medical Sciences | Recruiting | Poznan | Poland |
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| ID | Term |
|---|---|
| D006617 | Hip Dislocation |
| ID | Term |
|---|---|
| D004204 | Joint Dislocations |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Ropivacaine 0.2% for LFCB |
| Drug |
LFCB (0.1 mL/kg) with 0.2% ropivacaine |
|
| Ropivacaine 0.2% for L-ESPB | Drug | Lumbar ESPB (0.25ml/kg) with 0.2% ropivacaine |
|
| Ropivacaine 0.2% for S-ESPB | Drug | Sacral ESPB (0.25ml/kg) with 0.2% ropivacaine |
|
| 4 hours after surgery |
| Numerical Rating Scale [range 0:10] | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) | 8 hours after surgery |
| Numerical Rating Scale [range 0:10] | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) | 12 hours after surgery |
| Numerical Rating Scale [range 0:10] | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) | 24 hours after surgery |
| Numerical Rating Scale [range 0:10] | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) | 48 hours after surgery |
| NLR | neutrophile to lymphocyte ratio | 12 hours after surgery |
| NLR | neutrophile to lymphocyte ratio | 24 hours after surgery |
| NLR | neutrophile to lymphocyte ratio | 48 hours after surgery |
| PLR | platelet to lymphocyte ratio | 12 hours after surgery |
| PLR | platelet to lymphocyte ratio | 24 hours after surgery |
| PLR | platelet to lymphocyte ratio | 48 hours after surgery |
| D025981 |
| Hip Injuries |
| D000588 |
| Amines |