Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension

The Novel Use of Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension in Patients With Surgical Sepsis, a Double Blind Randomized Controlled Trial

researchers aim to evaluate the influence of prophylactic noradrenaline infusion on post-induction hypotension

If post-induction hypotension is not addressed promptly, it can lead to severe complications such as reduced blood flow, acute kidney damage, and myocardial ischemia. As a result, early detection and proactive intervention are crucial. Researchers of the current study decided to investigate impact of noradrenaline administered as a prophylaxis on post induction hypotension

Inclusion Criteria:

• Adult patients with sepsis undergoing source control surgery.

Exclusion Criteria:

• Patient refusal
• Patient with cardiac pathology ( ischemic heart disease or heart failure)
• Preoperative hemodynamic instability (defined as MAP < 65 mmHg)
• Rapid sequence induction