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Caffeine extracted from green tea to abort acute attack of Migraine
Caffeine tablets extracted from green tea can be used as caffeinated drinks to decrease intensity of migraine attacks
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Caffeine group | Experimental | Caffeine group added to standard treatment |
|
| Control group | Active Comparator | Standard treatment (NSAIDS, Triptans, or Acetaminophen) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Caffeine (200 mg) | Drug | caffeine tablets |
| |
| triptans |
| Measure | Description | Time Frame |
|---|---|---|
| To reduce the severity of migraine attack | using Visual analogue scale | Three years |
| Measure | Description | Time Frame |
|---|---|---|
| To evaluate the effect of oral caffeine in reducing pain associated with acute migraine attacks among patients attending Headache Clinic, Ain Shams University hospital via Visual analogue scale | To assess the pain reduction through visual analogue scale | Three year |
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Inclusion Criteria:
Patients suffering from migraine with aura, migraine without aura, episodic, and chronic migraine according to ICHD-3 diagnosis will be legible for the study.
Exclusion Criteria:
Patients who have history of any cardiac dysrhythmia, hypertension, ischemic heart disease, active peptic ulcer disease, inflammatory bowel disease, obsessive compulsive disorder, pregnancy, breast-feeding, renal failure, hepatic failure, sleep disorder, mental retardation, and history of substance abuse that prevent them from cooperating with us during the study Patients who had headache due to: Cluster headache, trigeminal neuralgia, glossopharyngeal neuralgia, headache secondary to trauma, cranial disorder, vascular disorder, infection, or mass lesion, will also be excluded
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nourhan Nader Elguindy, Masters degree | Contact | 00201128215952 | nourhanelguindy@gmail.com | |
| Diaa Marzouk Abdelhamid, PhD | Contact | 00201200678440 | diaamarzouk@yahoo.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ainshams university | Recruiting | Cairo | 11769 | Egypt |
Abstract
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| Drug |
Sumatriptan |
|
| NSAID (Nonsteroidal anti-inflammatory drugs) | Drug | Aspirin 250 mg, 81 mg, 75 mg |
|
| Paracetamol (acetaminophen) | Drug | Paracetamol 250 mg |
|
| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D002110 | Caffeine |
| D014363 | Tryptamines |
| D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| D000082 | Acetaminophen |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D015306 | Biogenic Monoamines |
| D001679 | Biogenic Amines |
| D000588 | Amines |
| D009930 | Organic Chemicals |
| D007211 | Indoles |
| D018712 | Analgesics, Non-Narcotic |
| D000700 | Analgesics |
| D018689 | Sensory System Agents |
| D018373 | Peripheral Nervous System Agents |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D000893 | Anti-Inflammatory Agents |
| D045506 | Therapeutic Uses |
| D018501 | Antirheumatic Agents |
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |
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