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| Name | Class |
|---|---|
| Tongji Hospital | OTHER |
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This study is an open-label, prospective, exploratory clinical trial that includes a dose escalation phase and a dose expansion phase, aimed at evaluating the safety, cell dynamics, and preliminary efficacy of GT719 cells in adult participants with recurrent/refractory antibody-mediated neurological immune diseases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GT719 Injection treatment group | Experimental | GT719 Injection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| GT719 Injection | Biological | GT719 Injection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence and severity of adversed events | To characterize the safety profile of GT719 in patients with recurrent/refractory antibody-mediated neurological immune diseases as measured by the incidence and severity of adverse events | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics of GT719 cells | Survival time of GT719 cells after infusion of GT719 Injection | 24 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Daishi Tian | Contact | +8613607178809 | tiands@tjh.tjmu.edu.cn | |
| Wei Wang | Contact | +86-27-83662640 | wwang@tjh.tjmu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Wei Wang | Tongji Hospital | Principal Investigator |
| Daishi Tian | Tongji Hospital | Principal Investigator |
| Chuan Qin |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology | Recruiting | Wuhan | Hubei | China |
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| Tongji Hospital |
| Principal Investigator |