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Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CCS patients | Clinical patients referred for ischaemia testing (CMR/coronary angiogram) will undergo the respective counterpart as well so that patients will have undergone both CMR and invasive testing. |
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| Measure | Description | Time Frame |
|---|---|---|
| Quantitative Perfusion | Correlation of myocardial blood flow and perfusion reserve in CMR with invasively dervived fractional flow reserve (FFR), coronary flow reserve (CFR) and microcirculatory resistance (IMR) | assessment of CMR and invasive data within 24hours |
| Dual bolus vs dual sequence | Compare both CMR-derived quantitative perfusion for prediction of FFR/CFR/IMR | assessment of CMR and invasive data within 24hours |
| Measure | Description | Time Frame |
|---|---|---|
| Strain | Correlation of segmental perfusion and myocardial strain | baseline CMR data |
| Tissue characterisation | Correlation of segmental perfusion and T1/T2/ECV/LGE |
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Inclusion Criteria:
Exclusion Criteria:
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All patients referred to the clinical service for ischaemia evaluation
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sören Jan Backhaus, MD | Contact | 06032-996-2620 | s.backhaus@kerckhoff-klinik.de | |
| Andreas Rolf, MD | Contact | 06032-996-2620 | a.rolf@kerckhoff-klinik.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kerckhoff Klinik | Bad Nauheim | Hesse | 61231 | Germany |
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| baseline CMR data |
| Cardiovascular Hospitalisation (CVH) | CVH within 12 months | 12 months |