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The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need of preventing chronic emotional distress in YOD dyads through a feasible, acceptable and credible program, and ideally enhance resiliency and improve wellbeing and quality of life in both members of the dyad.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental: Experimental Patient-Caregiver Dyads | Experimental | There will be 6 sessions delivered via live video using Zoom. Content will be primarily skills. |
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| Control Patient-Caregiver Dyads | Active Comparator | There will be 6 sessions delivered via live video using Zoom. Content will be primarily educational. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Resilient Together-YOD | Behavioral | This is a 6 session dyadic (patient and spousal care-partner) intervention that teaches resiliency and interpersonal communication skills early after YOD diagnoses. It aims to decrease heightened symptoms of depression and anxiety among dyads to help them engage in important decisions around long term care-planning and optimize adjustment. The goal is to equip dyads with the necessary skills to cope and engage in meaningful, challenging conversations around care-planning, symptom deterioration, work/family planning to improve well-being in both members of the dyad. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Emotional Distress | Hospital Depression and Anxiety Scale total score (HADS); 0-21 for each subscale (anxiety and depression), higher scores indicate greater anxiety or depression | 0 weeks, 6 weeks, 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Resiliency Factors (Mindfulness) | Cognitive and Affective Mindfulness Scale (CAMS); 12-48, higher scores indicate greater perceived mindfulness | 0 weeks, 6 weeks, 12 weeks |
| Change in Resiliency Factors (Individual Coping) |
| Measure | Description | Time Frame |
|---|---|---|
| Global Impressions of Change | Modified Global Impressions of Chance (MGIC); 1-7, higher scores indicate greater perceived change in outcomes | 6 weeks, 12 weeks |
| Cognition | Montreal Cognitive Assessment (MoCA); 0-30, lower scores indicate greater cognitive dysfunction |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ana-Maria Vranceanu, PhD | Contact | 617-724-4977 | avranceanu@mgh.harvard.edu | |
| Maggie L Syme, PhD, MPH | Contact | msyme@mgh.harvard.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital (MGH) | Recruiting | Boston | Massachusetts | 02114 | United States |
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| Health Enhancement Program-YOD | Behavioral | This is a 6 session program that will deliver educational information to dyads and will mimic the dose and duration of Resilient Together. The program will not teach any individual and dyadic interpersonal skills, but will contain education on psychological distress and healthy behaviors. Sessions will also be delivered virtually. |
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Measure of Current Status Part A (MOCS-A) Assertiveness and Coping Confidence subscales; Subscale scores: 0-4; higher scores indicate greater perceived ability to cope
| 0 week, 6 weeks, 12 weeks |
| Change in Resiliency Factors (Mindfulness Utilization) | Applied Mindfulness Scale (AMPS); 0-60, higher scores indicate greater use of mindfulness practices. | 0 weeks, 6 weeks, 12 weeks |
| Changes in Interpersonal Factors (Dyad Coping) | Dyadic Coping Inventory (DCI); 37-185, higher scores indicate greater perceived coping in the context of a relationship | 0 weeks, 6 weeks, 12 weeks |
| Changes in Resiliency Factors (Perceived Social Support) | Multidimensional Scale of Perceived Social Support (MSPSS); 12-84, higher scores indicate greater perceived social support from family, friends, and significant others | 0 weeks, 6 weeks, 12 weeks |
| Changes in Resiliency Factors (Values-based Living) | Valuing Questionnaire (VQ); Progress and Obstruction Subscale Scores: 0-30, higher scores indicate living in greater accordance with one's values | 0 weeks, 6 weeks, 12 weeks |
| 0 weeks |