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This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response.
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response. The findings will help identify which types of jaggery have lower glycemic impact, contributing to better dietary choices for glycemic control.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single group (cross over) | Active Comparator | Participants will receive all test interventions (2 different varieties of jaggery and a glucose reference) in a randomized sequence with appropriate washout periods between each session. Blood glucose levels will be measured after each test food to determine and compare glycemic index values. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Golden sugarcane jaggery | Other | Participants will consume a standardized portion of jaggery Type A providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period. |
| Measure | Description | Time Frame |
|---|---|---|
| Glycemic Index (GI) of Different Types of Jaggery | The incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of each type of jaggery, expressed as a percentage of the glucose reference. | Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session. |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial Blood Glucose Response Curve | Blood glucose levels at each time point following consumption of jaggery types and glucose, to assess the shape and peak of glycemic response. | Same as primary outcome (0-120 minutes). |
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Inclusion Criteria:Participants should be clinically healthy, as determined by their medical records and verbal history. Only individuals with normal fasting blood glucose levels (70-99 mg/dL) during screening will be eligible -
Exclusion Criteria:1) Participants must not have any chronic disease, not be taking any medications that influence carbohydrate metabolism (such as corticosteroids or metformin), and should be non-smokers and non-alcoholics.
2) Pregnant or lactating female participants, as well as any person with gastrointestinal, metabolic, or endocrine disease (e.g., thyroid disease, PCOS, IBD), will be excluded.
3) Also, subjects with a history of recent acute illness (within the last 2 weeks) will be deferred.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Naseer Ahmed | Contact | 03305485960 | dr.naseer99@mail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rehman Medical Institue | Peshawar | Khyber Pakhtunkhwa | 092 | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9743703 | Background | Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food Nutr Pap. 1998;66:1-140. No abstract available. | |
| Background | International Diabetes Federation. (2021). *IDF Diabetes Atlas* (10th ed.). Brussels, Belgium: IDF. | ||
| 6259925 |
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| Dark brown sugarcane jaggery | Other | Participants will consume a standardized portion of jaggery Type B providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period. |
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| Background |
| Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6. doi: 10.1093/ajcn/34.3.362. |