Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to investigate the effects of quadriceps focused interventions on knee function and biomechanics in adolescent patients with anterior cruciate ligament reconstruction (ACLR)
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Additional neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR) | Experimental | Participants receive a 6-week NMES intervention from week 1 to week 6 post-surgery, followed by a 10-week BFR intervention from week 7 to week 16. Participants also receive standard rehabilitation care as part of their routine postsurgical recovery process. |
|
| Standard rehabilitation | Active Comparator | Participants receive standard rehabilitation care as part of their routine postsurgical recovery process. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| NMES and BFR | Other | NMES is applied when patients perform quadriceps strengthening exercises. BFR is applied during compound exercises. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Peak force as measured by isometric knee extension force test | Isometric knee extension force will be measured with a dynamometer. | 16 weeks post surgery |
| Force steadiness as measured by isometric knee extension force test | Isometric knee extension force will be measured with a dynamometer | 16 weeks post surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Sagittal plane peak angle at the hip during countermovement jump landing | Motion analysis will be conducted using the cloud-based OpenCap application | 16 weeks post surgery |
| Sagittal plane peak angle at the knee during countermovement jump landing |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Alexandra M Abbott, MD | Stanford School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford Medicine Children's Health | Recruiting | Sunnyvale | California | 94087 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12635796 | Background | Ohta H, Kurosawa H, Ikeda H, Iwase Y, Satou N, Nakamura S. Low-load resistance muscular training with moderate restriction of blood flow after anterior cruciate ligament reconstruction. Acta Orthop Scand. 2003 Feb;74(1):62-8. doi: 10.1080/00016470310013680. | |
| 20592480 | Background | Kim KM, Croy T, Hertel J, Saliba S. Effects of neuromuscular electrical stimulation after anterior cruciate ligament reconstruction on quadriceps strength, function, and patient-oriented outcomes: a systematic review. J Orthop Sports Phys Ther. 2010 Jul;40(7):383-91. doi: 10.2519/jospt.2010.3184. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000070598 | Anterior Cruciate Ligament Injuries |
| ID | Term |
|---|---|
| D007718 | Knee Injuries |
| D007869 | Leg Injuries |
| D014947 | Wounds and Injuries |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Standard physical therapy | Other | Standard physical therapy (week 1-16) includes interventions for typical impairments following ACLR. The initial phase will focus on pain and effusion control, restoration of knee range of motion, followed by gait normalization, lower extremity strength training, then running and plyometrics. |
|
Motion analysis will be conducted using the cloud-based OpenCap application
| 16 weeks post surgery |
| Sagittal plane peak angle at the ankle during countermovement jump landing | Motion analysis will be conducted using the cloud-based OpenCap application | 16 weeks post surgery |