Bevacizumab Versus Triamcinolone Acetonide for the Treatment of Keloids.

Efficacy of Intralesional Bevacizumab Versus Intralesional Triamcinolone Acetonide Injection in the Treatment of Keloids.

The study compares the efficacy and safety of intralesional bevacizumab versus corticosteroids for the treatment of keloids. Assessment will be done clinically by the use of Modified Vancouver Scar Scale. Erythema index will be measured by spectrophotometry. The levels of Vascular Endothelial Growth Factor, collagen type 1 and collagen type 3 in the lesions before and after each treatment modality.

Inclusion Criteria:

• Patients with keloids (post-traumatic, any site, any duration)
• Age >18 years
• Patients who didn't receive any treatment for the lesions in the past 6 weeks

Exclusion Criteria:

• Patients who are pregnant, willing to get pregnant or lactating
• History of any liver or renal disease
• History of any cardiovascular disease
• History of hypertension
• History of thrombo-embolic events
• Known cases of bleeding disorders
• History of peptic ulcer
• Patients who underwent any surgeries in the last month