Tranexamic Acid to Reduce Blood Loss in Women Having Planned Cesarean Section

Role of Tranexamic Acid in Control of Intraoperative Blood Loss in Women Undergoing Elective Cesarean Section

This clinical trial was done to find out if tranexamic acid (TXA) can safely reduce the amount of blood loss during cesarean (C-section) deliveries. Heavy bleeding is a major risk during childbirth, especially in C-sections, and can be life-threatening.

The main question this study wanted to answer was:

Does giving tranexamic acid before surgery reduce the amount of blood lost during a planned C-section?

In this study, 68 women who were scheduled for elective (planned) C-section deliveries were randomly assigned to receive either tranexamic acid or a placebo (a look-alike substance with no medicine in it) before surgery. The medication was given by slow injection just 15 minutes before the operation.

All surgeries followed the same procedure and were done by experienced obstetric surgeons. The amount of blood lost during surgery was carefully measured and compared between the two groups.

The goal was to find a simple and safe way to lower the risk of blood loss and its complications during C-sections, improving outcomes for mothers.

Inclusion Criteria:

• Women age 20-45 years
• at 37-40 weeks of gestation (on LMP)
• Planned to undergo cesarean section under spinal anesthesia

Exclusion Criteria:

• Women with previous history of thromboembolic events
• Allergy to tranexamic acid
• Women with morbidly adherent placenta (on antenatal USG)